Results 61 to 70 of about 4,462,462 (332)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Mechanical properties of slag sand mixture used in road pavements

open access: yesMagazine of Civil Engineering, 2021
Today the road has become a necessity and an important factor in the economic and social development of nations. Algeria knows the realization of many grandiose road projects that required large quantities of noble materials such as aggregates and ...
Cherfa Hayet   +3 more
doaj   +1 more source

The long road to improvement in modelling & managing engineering processes (MMEP) [PDF]

open access: yes, 2015
Managing complex engineering design processes is a challenge for industry, which is looking to academia to provide tools and methods to support them. The Modelling and Managing of Engineering Processes Special Interest Group of the Design Society aims
Eckert, Claudia, Gericke, Kilian
core  

An overview of ground-penetrating radar signal processing techniques for road inspections [PDF]

open access: yes, 2016
Ground-penetrating radar (GPR) was firstly used in traffic infrastructure surveys during the first half of the Seventies for testing in tunnel applications.
Benedetto, Andrea   +3 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Performance analysis and prediction of asphalt pavement containing municipal solid waste incineration bottom ash aggregate based on MEPDG

open access: yesScientific Reports
Municipal solid waste incinerator (MSWI) bottom ash (BA) is the main product of municipal solid waste after being burned. MSWI bottom ash aggregate (BAA) which is made from processed BA can be used in road engineering due to its strength and gradation ...
Yu Sun   +5 more
doaj   +1 more source

Coal tar, material used in soil improvement for use in road engineering

open access: yes, 2016
Coal tar is a by-product of coal distillation in the absence of oxygen to obtain metallurgical coke; its colour varies from dark coffee to black, slightly viscous and its density is greater than that of water.
R. Ochoa Díaz, A. Montanez, J. Cuentas
semanticscholar   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Pavement Engineering for Forest Roads [PDF]

open access: yesCroatian journal of forest engineering, 2020
Pavement is an essential component of roads as it carries the traffic and provides the required riding comfort. Considering that numerous forest roads are approaching their end of life, the critical issue is identifying the best rational pavement design methods to reengineer existing and build new pavement structures.
openaire   +4 more sources

Kesadaran Hukum Masyarakat Pengguna Jalan di Kota Denpasar [PDF]

open access: yes, 2013
Legal awareness of road users especially users of motorcycles is a process of assessment of the traffic law. Every human being has the legal awareness, the problem is the level of awareness, there is a high, medium and low.
TAGEL, D. P. (DEWA)
core   +3 more sources

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