Results 61 to 70 of about 231,296 (310)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Automatic Estimation of Excavation Volume from Laser Mobile Mapping Data for Mountain Road Widening
Remote Sensing, 2013 Roads play an indispensable role as part of the infrastructure of society. In recent years, society has witnessed the rapid development of laser mobile mapping systems (LMMS) which, at high measurement rates, acquire dense and accurate point cloud data ...
Massimo Menenti +4 more
doaj +1 more source
Materials Research Express, 2022 It is difficult to determine a reasonable mixing temperature for WMA based solely on the viscosity-temperature relationship of the binder, as is the case for HMA, and it is a more reasonable solution to determine the mixing temperature of WMA by the ...
Liming Wang +4 more
doaj +1 more source
TERRA E-News (January 2015, vol. 9, no. 1) [PDF]
, 2015 Articles include: WisDOT explores higher recycled content in asphalt pavements; Member Highlights; Iowa partnership studying road foundation stabilization technologies; New software will aid design of concrete pavements in Minnesota; TERRA Pavement ...
Transportation Engineering and Road Research Alliance (TERRA)
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Applied Sciences, 2017 The objective of this investigation is to prepare the shape memory hydrogenated epoxy resin used for asphalt mixtures (SM-HEP-AM) and study its properties.
Biao Ma +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Laboratory Evaluation of Rejuvenating Agent on Reclaimed SBS Modified Asphalt Pavement
Applied Sciences, 2017 To evaluate the effect of rejuvenating agent on reclaimed SBS (styrene-butadiene-styrene) modified asphalt pavement (RSMAP) material, different tests of asphalt and mixtures were conducted.
Jie Wang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Mechanical Engineering Aspects of Road Construction [PDF]
Proceedings of the Institution of Mechanical Engineers, 1913 n ...
openaire +1 more source