Results 101 to 110 of about 148,828 (311)

Extracting Main Center Pattern from Road Networks Using Density-Based Clustering with Fuzzy Neighborhood

open access: yesISPRS International Journal of Geo-Information, 2019
The spatial pattern is a kind of typical structural knowledge that reflects the distribution characteristics of object groups. As an important semantic pattern of road networks, the city center is significant to urban analysis, cartographic ...
Xiaojie Cui   +6 more
doaj   +1 more source

Investing for Reliability and Security in Transportation Networks [PDF]

open access: yes
Alternative transportation investment policies can lead to very different network forms in the future. The desirability of a transportation network should be assessed not only by its economic efficiency but also by its reliability and security, because ...
Lei Zhang, David Levinson
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Online Multi-Skilled Task Assignment on Road Networks

open access: yesIEEE Access, 2019
With the development of smart phones and online to offline, spatial platforms, such as TaskRabbit, are getting famous and popular. Tasks on these platforms have three main characters: they are in real-time dynamic scenario, they are on the road networks,
Yu Liang   +3 more
doaj   +1 more source

Road Pricing with Autonomous Links [PDF]

open access: yes
This research examines road pricing on a network of autonomous highway links. By autonomous it is meant that the links are competitive and independent, with the objective of maximizing their own profits without regard for either social welfare or the ...
Lei Zhang, David Levinson
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Economics of Road Network Ownership [PDF]

open access: yes
This paper seeks to understand the economic impact of centralized and decentralized ownership structures and their corresponding pricing and investment strategies on transportation network performance and social welfare for travelers.
Lei Zhang, David Levinson
core  

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