Results 101 to 110 of about 9,513,060 (240)
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
, 2009 copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department for Transport, Road Accident Statistics Branch
core +2 more sources
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
Rheology and Infrared Spectrum of Diatomite Asphalt Concrete
Kuangchan zonghe liyongThis is an article in the field of ceramics and composites. In order to study the influence of diatomite content on the physical properties, rheological properties and road performance of asphalt mixtures, the basic physical tests, rheological tests ...
Yi XU, Yin ZHANG
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
BuildingsThis paper reviews the research progress and development of aluminate long afterglow luminescent materials in the field of road marking, especially the study of rare earth ion-activated strontium aluminate (SrAl2O4: Eu2+, Dy3+)-based long afterglow ...
Fangzhi Zhang +7 more
doaj +1 more source
Ethical Foreground and Background in Adult Educator Work
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
Phase-Change/Salt-Based Slow-Release Composite Material for Anti-Icing and Snow-Melting
BuildingsCurrently, self-desiccating asphalt mixtures on roads mainly incorporate phase-change materials or salt-based slow-release agents individually for de-icing. However, pure phase-change material mixtures have limited anti-freezing efficiency and short heat-
Chuanshan Wu +4 more
doaj +1 more source
, 2006 copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of Transport, Road Accident Statistics Branch
core
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source