Results 81 to 90 of about 1,546,705 (251)

The road to lightweight performance

Reinforced Plastics, 2008
With over 400 attendees and 60 plus papers, eight keynotes, and one panel discussion, the 2008 Society of Plastics Engineers (SPE) Automotive Composite Conference and Exposition (ACCE)'s ‘The Road to Lightweight Performance’ convened in Troy, Michigan, in the USA for three full days of presentations, panel discussions and networking receptions.
null Mike, Pam Brady
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Study of Low-Content Epoxy Asphalt Mixture Applied to the Road

Buildings
To realize the application of epoxy asphalt concrete on roads and solve the problem of the high cost of epoxy asphalt concrete and the causes of bulging in the construction process, a low-content epoxy asphalt mixture was experimentally studied ...
Xiaodong Li, Chuanxi Luo, Shaohuai Wang, Xiang Long, Yan Wang, Jian Li, Mu He   +6 more
doaj   +1 more source

Multiple Object Tracking in Urban Traffic Scenes with a Multiclass Object Detector

, 2018
Multiple object tracking (MOT) in urban traffic aims to produce the trajectories of the different road users that move across the field of view with different directions and speeds and that can have varying appearances and sizes.
B Coifman, HW Kuhn, J-P Jodoin, K Bernardin, Luis M. Fuentes, PF Felzenszwalb, RE Kalman, S Aslani   +7 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Influence of Ultra-Fine Iron Tailings Sand on Performance of Cement-Stabilized Macadam Base

Zhongwai Gonglu
To study the application potential of ultra-fine iron tailings sand (UITS) as a road base material, this paper conducted unconfined compressive strength (UCS) tests and freezing and thawing tests to systematically analyze the effects of UITS content and ...
MENG Delong, LI Hongzhen, CHEN Fushen, WANG Keran, JIANG Yuntao, CHEN Lei, FENG Zhuangzhuang   +6 more
doaj   +1 more source

Quantification and description of braking during mountain biking using a novel brake power meter : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Sport & Exercise at Massey University, Palmerston North, New Zealand [PDF]

, 2017
Olympic format cross country mountain biking is both physically and technically demanding. The demands of this cycling genre are in contrast to road cycling because of the demanding off-road terrain.
Miller, Matthew Curtis
core  

Aerodynamic Performance of Road Vehicles

International Journal of Innovative Technology and Exploring Engineering, 2020
Aerodynamic drag has been experimentally estimated for scale models of a passenger car and a commercial truck in a wind tunnel. Polished surface has resulted up to 15 % reduction in drag force and add-on has resulted in 57% increase in drag force of a car model whereas 2.6 % reduction in drag force has resulted by using deflector in a commercial truck ...
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source