Results 61 to 70 of about 12,163 (214)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Study of Low-Content Epoxy Asphalt Mixture Applied to the Road

Buildings
To realize the application of epoxy asphalt concrete on roads and solve the problem of the high cost of epoxy asphalt concrete and the causes of bulging in the construction process, a low-content epoxy asphalt mixture was experimentally studied ...
Xiaodong Li, Chuanxi Luo, Shaohuai Wang, Xiang Long, Yan Wang, Jian Li, Mu He   +6 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Influence of Ultra-Fine Iron Tailings Sand on Performance of Cement-Stabilized Macadam Base

Zhongwai Gonglu
To study the application potential of ultra-fine iron tailings sand (UITS) as a road base material, this paper conducted unconfined compressive strength (UCS) tests and freezing and thawing tests to systematically analyze the effects of UITS content and ...
MENG Delong, LI Hongzhen, CHEN Fushen, WANG Keran, JIANG Yuntao, CHEN Lei, FENG Zhuangzhuang   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

AI-Driven Comprehensive SERS-LFIA System: Improving Virus Automated Diagnostics Through SERS Image Recognition and Deep Learning

Biosensors
Highly infectious and pathogenic viruses seriously threaten global public health, underscoring the need for rapid and accurate diagnostic methods to effectively manage and control outbreaks.
Shuai Zhao, Meimei Xu, Chenglong Lin, Weida Zhang, Dan Li, Yusi Peng, Masaki Tanemura, Yong Yang   +7 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Analysis of Vibration Characteristics of Spatial Non-Uniform Tensioned Thin-Film Structures Based on the Absolute Nodal Coordinate Formulation

Micromachines
Due to their lightweight characteristics, spatial thin-film structures can generate vibrations far exceeding their film thickness when subjected to external loads, which has become a key factor limiting their performance.
Peng Sun, Jin Huang, Jiaying Zhang, Fanbo Meng, Pengbing Zhao   +4 more
doaj   +1 more source

Aerodynamic Performance of Road Vehicles

International Journal of Innovative Technology and Exploring Engineering, 2020
Aerodynamic drag has been experimentally estimated for scale models of a passenger car and a commercial truck in a wind tunnel. Polished surface has resulted up to 15 % reduction in drag force and add-on has resulted in 57% increase in drag force of a car model whereas 2.6 % reduction in drag force has resulted by using deflector in a commercial truck ...
openaire   +1 more source