Results 41 to 50 of about 12,826,919 (257)

Research on Road Performance of Solid-Waste-Based-Gelling-Agent-Stabilized Sub-Base

open access: yesEngineering Proceedings, 2023
To determine the road performance and optimum dosing of solid-waste-based gelling agents in road subgrade, we conducted unconfined compressive strength testing for clay, sandy soil, weathered sand, and crushed stone mixed with different proportions of ...
Tao Guo, Yueqiang Qi
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

Performance and Reinforcement Mechanism of Modified Asphalt Binders with Nano-Particles, Whiskers, and Fibers

open access: yesApplied Sciences, 2019
The asphalt binders could be modified to improve road perfo rmances by using various methods, and the reinforcement mechanisms are obviously different and quietly affect the road performances.
Xiangyang Xing   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The RaKJA Application for Designing Android the Based Road Section Performance

open access: yesJurnal Teknik Sipil
Performance analysis of road sections is usually carried out on road sections that have the potential for high traffic jams, then perform performance calculations and obtain recommendations for problems on these road sections.
Rindu Twidi Bethary   +2 more
doaj   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Road Performance of Fiber-Reinforced Semi-Flexible Pavement Materials

open access: yesZhongwai Gonglu
This paper aimed to investigate the reinforcement effects of basalt fiber, polyester fiber, and lignin fiber on semi-flexible pavement materials and study their applicability in different structural layers.
SUN Xuecong, WANG Hongchang, LIU Song
doaj   +1 more source

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