Results 221 to 230 of about 2,416,136 (291)

Factors associated with road traffic injury severity among victims retrieved by pre-hospital emergency services in Rwanda. [PDF]

F1000Res
Uwitonze E, Biracyaza E.
europepmc   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Assessing the global data availability and characteristics of eight risk factors for road traffic injury: an evaluation study across 194 countries/territories, 2000-2019. [PDF]

J Glob Health
Wang W, Hua J, Schwebel DC, Li J, Li L, Rao Z, Cheng P, Ning P, Hu G.   +8 more
europepmc   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

Phytotherapy Research, EarlyView.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao, Da Ke, Jian Ni, Yuan Yuan, Zhang Nan, Xiujun Dai, Heng Zhou   +6 more
wiley   +1 more source

Prehospital factors associated with mortality among road traffic injury patients: analysis of Cameroon trauma registry data. [PDF]

BMC Emerg Med
Ngekeng S, Kibu O, Oke R, Bassah N, Touko DA, Yost MT, Dissak-Delon F, Tendongfor N, Nguefack-Tsague G, Hubbard A, McCoy SI, Christie SA, Chichom-Mefire A, Juillard C.   +13 more
europepmc   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Identifying emerging hot spots of road traffic injury severity using spatiotemporal methods: longitudinal analyses on major roads in Ghana from 2005 to 2020. [PDF]

BMC Public Health
Mesic A, Damsere-Derry J, Feldacker C, Mooney SJ, Gyedu A, Mock C, Kitali A, Wagenaar BH, Wuaku DH, Afram MO, Larley J, Opoku I, Ekuban E, Osei-Ampofo M, Stewart B.   +14 more
europepmc   +1 more source

The Return of the Allis Shad (Alosa alosa) to the Lower Navigable Reaches of the Seine: Locks Play a Role

River Research and Applications, EarlyView.
ABSTRACT In France, it is estimated that shads (Alosa spp.) have lost 69% of their historical range, mainly due to disrupted river connectivity. After an absence of one century, signs of their return in the Seine River have been recorded over the past two decades: adult and juvenile specimens have been caught by anglers or recorded at video‐counting ...
Céline Le Pichon, Frédérique Bau, Armand Michelot, Evelyne Tales, Sébastien Grall, Eric Rochard   +5 more
wiley   +1 more source

Trends in lawyer use in road traffic injury compensation claims. [PDF]

PLoS One, 2020
Scollay CE, Berecki-Gisolf J, Grant GM.
europepmc   +1 more source