Results 101 to 110 of about 10,441 (309)
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
The value of time and forecasting of flowsin freight transportation [PDF]
This paper gives an overview of the current state of research and present own results in some areas regarding cost benefit analysis (CBA) for road infrastructure investments.
Erik Bergkvist
core
Advanced Science, EarlyView.A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu +5 more
wiley +1 more source
Competition and horizontal integration in maritime freight transport [PDF]
This paper develops a theoretical model for freight transport characterized by competition between means of transport (the road and maritime sectors), where modes are perceived as differentiated products.
Rafael Moner-Colonques +3 more
core
Advanced Science, EarlyView.This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu +7 more
wiley +1 more source
Adaptive stated preference analysis of shippers? transport and logistics choice [PDF]
In this paper we propose a micro analysis of freight transport demand. Current research concentrates with few exceptions on shippers? choice of a transport mode and offers consistent evidence on the importance of characteristics. However, with globalised
Simona Bolis, Rico Maggi
core
Advanced Science, EarlyView.Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole +17 more
wiley +1 more source
The welfare effects of freight travel time savings [PDF]
In this article we investigate the welfare effect of freight travel time savings. The general setup of this article is to suppose that transport operators face a constraint on minimum travel time and to examine what is occurring when this minimum travel ...
Jérôme Massiani
core +2 more sources
International road and rail freight transport: the impact of globalisation on activity levels
, 2010 This chapter establishes the recent trends in international trade volumes. It then aims to identify the main ways in which this trade growth has affected road and rail freight transport activity at the international level, and finally considers the ...
Leonardi, J. +4 more
core
Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants
Advanced Science, EarlyView.A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei +8 more
wiley +1 more source