Results 21 to 30 of about 33,999 (196)

Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence

open access: yesEmerging Microbes and Infections, 2018
A large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both EHEC and enteroaggregative E. coli (
Christina Lang   +6 more
doaj   +1 more source

Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)

open access: yesActa Neuropathologica Communications, 2018
Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms
Michael Burwinkel   +4 more
doaj   +1 more source

Differential Involvement of L-Type Calcium Channels in Epileptogenesis of Rat Hippocampal Slices during Ontogenesis

open access: yesNeurobiology of Disease, 2000
Organic calcium channel antagonists block epileptiform activity in adult tissue, suggesting an essential role of L-type channels in epileptogenesis in the mature CNS.
R. Köhling, H. Straub, E.-J. Speckmann
doaj   +1 more source

Seasonal and inter-annual variation of malaria parasite detection in wild chimpanzees

open access: yesMalaria Journal, 2018
Background Cross-sectional surveys of chimpanzee (Pan troglodytes) communities across sub-Saharan Africa show large geographical variation in malaria parasite (Plasmodium spp.) prevalence.
Doris F. Wu   +7 more
doaj   +1 more source

Seizure-related activity of intralaminar thalamic neurons in a genetic model of absence epilepsy

open access: yesNeurobiology of Disease, 2011
Absence seizures are characterized by bilateral spike-and-wave discharges (SWDs) in thalamo-cortical circuits. In view of clinical studies indicating a critical involvement of intralaminar thalamic nuclei, we thought it timely to characterize the ...
Ali Gorji   +4 more
doaj   +1 more source

Trends in socioeconomic inequalities in self-rated health in Germany: a time-trend analysis of repeated cross-sectional health surveys between 2003 and 2012

open access: yesBMJ Open, 2019
Objectives This study assessed the extent of educational and income inequalities in self-rated health (SRH) in the German adult population between 2003 and 2012 and how these inequalities changed over time.Design Repeated cross-sectional health interview
Benjamin Wachtler   +2 more
doaj   +1 more source

Fusaricidins, Polymyxins and Volatiles Produced by Paenibacillus polymyxa Strains DSM 32871 and M1

open access: yesPathogens, 2021
Paenibacilli are efficient producers of potent agents against bacterial and fungal pathogens, which are of great interest both for therapeutic applications in medicine as well as in agrobiotechnology.
Pascal Mülner   +8 more
doaj   +1 more source

Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review

open access: yesBMC Infectious Diseases, 2016
Background In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal disease in the elderly. However, vaccine-induced immunity wanes after a few years, and
Cornelius Remschmidt   +4 more
doaj   +1 more source

Domain-specific physical activity patterns and cardiorespiratory fitness among the working population: Findings from the cross-sectional German Health Interview and Examination Survey

open access: yesBMJ Open, 2020
Objectives This study aimed to investigate associations between occupational physical activity patterns (physical work demands linked to job title) and leisure time physical activity (assessed by questionnaire) with cardiorespiratory fitness (assessed by
Thomas Keil   +5 more
doaj   +1 more source

The effect of estrogen and progesterone on spreading depression in rat neocortical tissues

open access: yesNeurobiology of Disease, 2007
Although gender differences in the incidence of migraine with aura appear to be related to high circulating levels of ovarian hormones, the underlying mechanisms are not yet fully understood.
Martin Sachs   +3 more
doaj   +1 more source

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