Results 41 to 50 of about 22,325,925 (249)

Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control

BMC Infectious Diseases, 2017
Background Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are scarce.
Gerit Korr, Michael Thamm, Irina Czogiel, Christina Poethko-Mueller, Viviane Bremer, Klaus Jansen   +5 more
doaj   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

HERV-K(HML-2), the best preserved family of HERVs: endogenisation, expression and implications in health and disease

Frontiers in Oncology, 2013
Retroviruses that have the ability to infect germ line cells can become an integral and inherited part of the host genome. About 8% of the human chromosomal DNA consists of sequences derived from infections by retroviruses that presumably circulated 2-40
Oliver eHohn, Kirsten eHanke, Norbert eBannert   +2 more
doaj   +1 more source

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

SARS-CoV-2 seroconversion in children attending daycare versus adults in Germany between October 2020 and June 2021

Communications Medicine, 2023
Background: Data on seroconversion rates after SARS-CoV-2 infection in young children (
Ulrike Kubisch, Anna Sandoni, Juliane Wurm, Anja Schienkiewitz, Martin Schlaud, Tim Kuttig, Bianca Finkel, Susanne Jordan, Julika Loss   +8 more
doaj   +1 more source

Structural Changes and Transport Properties of YBa2Cu3O7 Locally Modified by a He+ Focused Ion Beam

Advanced Science, EarlyView.
The structure and the electric transport properties of YBa2Cu3O7 modified with 30 keV He+${\rm He}^{+}$ ions depend on the irradiation dose and lateral size of the irradiated area, as shown by low‐temperature resistivity measurements, diffraction with a nanofocused X‐ray beam and atomic force microscopy.
Ross Carter, Robin Hutt, Paul Zimmermann, Ainur Abukaev, Jan Ullmann, Simon Koch, Christoph Schmid, Manfred Burghammer, Reinhold Kleiner, Dieter Koelle, Edward Goldobin, Ivan A. Zaluzhnyy   +11 more
wiley   +1 more source

Prevalence of Chlamydia trachomatis infection in women, heterosexual men and MSM visiting HIV counselling institutions in North Rhine-Westphalia, Germany - should Chlamydia testing be scaled up?

BMC Infectious Diseases, 2016
Background Patients asking for a free anonymous HIV test may have contracted other sexually transmitted infections (STIs) such as Chlamydia trachomatis, yet Chlamydia prevalence in that population is unknown. This study aimed to assess the prevalence and
Anne Lallemand, Viviane Bremer, Klaus Jansen, Stine Nielsen, Dieter Münstermann, Andreas Lucht, Carsten Tiemann   +6 more
doaj   +1 more source

Characteristics of the Top 50 Most‐Cited Arthroscopic Remplissage Articles Reveal Growing Recognition But Persistent Knowledge Gaps

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To identify and examine the article, author, and journal characteristics of the top 50 most‐cited articles on the arthroscopic remplissage procedure for the treatment of anterior shoulder instability in the field of orthopaedic sports medicine.
Brian S. Tao, Ross Clarke, Kevin A. Hao, Antonio Cusano, John D. Kelly IV, Robert L. Parisien, Richard Ma, Xinning Li   +7 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Tensions of Sustainability Logics: Performance of a Company Utilizing a Sustainable Business Model

Business Strategy and the Environment, EarlyView.
ABSTRACT In recent years, companies have used sustainable business models to gain a competitive advantage. However, there are tensions due to the inconsistency between social, environmental, and economic logic in sustainable business models, making it difficult for companies to change. To understand the existing tensions and interactions between logics,
Ann‐Kristin Thienemann
wiley   +1 more source