Results 61 to 70 of about 3,704,322 (286)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Master assisted cooperative control of human and robot [PDF]

, 1996
A cooperative control approach between human and robot takes an important role to carry out various tasks in hazardous environments or space. In this case, a robot is operated based on the cooperation between direct human control and autonomous robot ...
Inoue, Hiroyuki, E. Inoue, Noritsugu, Toshiro, T. Noritsugu   +3 more
core   +1 more source

TRADR Project: Long-Term Human-Robot Teaming for Robot Assisted Disaster Response

, 2015
International audienceThis paper contains a description of the project TRADR: Long-Term Human-Robot Teaming for Robot Assisted Disaster Response. As robotic disaster relief systems are still scarce, any incident serious enough to render robot involvement
Neerincx, M, Hindriks, Koen, Gianni, Mario, de Greeff, J, Worst, Rainer, Neerincx, Mark, Gianni, M, Pirri, F, Colas, Francis, Kruijff-Korbayová, I, Svoboda, Tomáš, Worst, R, Kruijff-Korbayová, Ivana, Colas, F, Hindriks, K, Ögren, Petter,, Svoboda, T, Ögren, Petter   +17 more
core   +2 more sources

Task-oriented and Purposeful Robot-Assisted Therapy [PDF]

, 2007
Robot-assisted therapy devices are available for rehabilitation of persons after stroke, which is the leading cause of disability among adults in the United States (AHA 2006, Volpe et al. 2002). Improving upper extremity function after stroke is critical for performance of one’s life-role and the completion of unilateral and bilateral activities of ...
Michelle J., Kimberly J., John Anderson, Dominic Nathan, Elaine Strachota, Judith Kosasih, Jayne Johnston, Roger O.   +7 more
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Effects of robot-assisted gait training in chronic stroke patients treated by botulinum toxin-a: A pivotal study

, 2018
ObjectiveTo investigate combined effects of robot-assisted training (RAT) and physical therapy versus physical therapy only on balance and gait function of chronic stroke patients after botulinum toxin-A (BoNT-A ...
Tugba, Gokbel, Melike, Akarsu, Erbil, Dursun, DURSUN, NİGAR, Murat, Topcu Hasan, Cagla, Karacan, Mehmetali, Ciftci Can, Merve, Akyuez, Akay, Ozturk   +8 more
core   +1 more source

Effects of Impedance Reduction of a Robot for Wrist Rehabilitation on Human Motor Strategies in Healthy Subjects during Pointing Tasks [PDF]

, 2011
Studies on human motor control demonstrated the existence of simplifying strategies (namely `Donders' law') adopted to deal with kinematically redundant motor tasks.
Campolo, Domenico, Domenico Campolo, Eugenio Guglielmelli, Formica, Domenico, Guglielmelli, Eugenio, Maria Scorcia, Nevio Luigi Tagliamonte, Domenico Formica, Scorcia, Maria, Tagliamonte, Nevio Luigi   +9 more
core   +1 more source

Effects of robot-assisted hand function therapy on brain functional mechanisms: a synchronized study using fNIRS and sEMG

Frontiers in Medicine
BackgroundRobot-assisted hand function therapy is pivotal in the rehabilitation of patients with stroke; however, its therapeutic mechanism remains elusive.
Changfeng Cheng, Tiantian Liu, Beibei Zhang, Xubo Wu, Zhenwang Song, Zhongzhi Zhao, Xue Ren, Minjun Zhao, Yajuan Su, Jiening Wang   +9 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Effects of robot-assisted upper limb rehabilitation on daily function and real-world arm activity in patients with chronic stroke: a randomized controlled trial

, 2017
Objective: To compare the outcome of robot-assisted therapy with dose-matched active control therapy by using accelerometers to study functional recovery in chronic stroke patients. ;Design: Prospective, randomized, controlled trial.
Liao, Wan-wen; Wu, Ching-yi; Hsieh, Yu-wei; Lin, Keh-chung; Chang, Wan-ying
core   +1 more source