Results 61 to 70 of about 572,179 (346)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Surface-Roughness Prediction Based on Small-Batch Workpieces for Smart Manufacturing: An Aerospace Robotic Grinding Case Study

open access: yesApplied Sciences
Small-batch workpieces in smart manufacturing demand process parameter modeling, but existing models lack analysis across varying sample sizes and runtime conditions.
Yi’nan Xiao   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Camera-LiDAR Fusion Method with Feature Switch Layer for Object Detection Networks

open access: yesSensors, 2022
Object detection is an important factor in the autonomous driving industry. Object detection for autonomous vehicles requires robust results, because various situations and environments must be considered.
Taek-Lim Kim, Tae-Hyoung Park
doaj   +1 more source

Robot autonomous navigation [PDF]

open access: yes, 1997
Autonomous vehicle navigation is a very popular research area in the vision and control field. Based on Prof. Dickmanns' philosophy, we implement a navigation algorithm on thc small robot.
Feng, Xiaolin, Liu, Wenhai
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

A Novel SDN-Based Application-Awareness Mechanism by Using Deep Learning

open access: yesIEEE Access, 2020
With the rapid development of the Internet of Things (IoT) and smart cities, more and more types of applications have been emerging. In fact, different applications have different features and different requirements on services. In order to satisfy users'
Nan Hu   +3 more
doaj   +1 more source

A Tandem Robotic Arm Inverse Kinematic Solution Based on an Improved Particle Swarm Algorithm

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The analysis of robot inverse kinematic solutions is the basis of robot control and path planning, and is of great importance for research. Due to the limitations of the analytical and geometric methods, intelligent algorithms are more advantageous ...
Guojun Zhao   +18 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

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