Results 111 to 120 of about 12,092,226 (295)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Analysis on structured stability of highly nonlinear pantograph stochastic differential equations

open access: yesSystems Science & Control Engineering, 2019
This paper investigates the structured stability and boundedness of highly nonlinear hybrid pantograph stochastic differential equations (PSDEs). The main contribution of this paper is to take the different structures into account to establish the ...
Mingxuan Shen   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Regulation and robust stabilization: a behavioral approach [PDF]

open access: yes, 2010
In this thesis we consider a number of control synthesis problems within the behavioral approach to systems and control. In particular, we consider the problem of regulation, the H! control problem, and the robust stabilization problem. We also study the
Fiaz, Shaik,, Fiaz, Shaik
core   +19 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Robust Control: A Note on the Timing of Model Uncertainty [PDF]

open access: yes
In this note a one-state, one-control variable quadratic linear problem with robust control and discount factor is developed to examine the optimal response of the first-period control to changes in future model uncertainty.
Arnulfo Rodriguez
core  

Comparison of selected tracking control algorithms for PMSM drive

open access: yesScientific Journal of Gdynia Maritime University, 2017
This paper presents comparison of four selected tracking control algorithms. The simulated plant is a PMSM drive with additional well-balanced inertia load and a point mass, which is moving radially.
Ł. Skarbek
doaj  

DISCRETE-TIME ROBUST CONTROL FOR ROBOT-MANIPULATOR [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2013
The problem of robot-manipulator control is considered under uncertainty in robot dynamic parameters and input noise. The linear discrete-time regulator is proposed for desired motion stabilization of robot-manipulator.
S. V. Gusev
doaj  

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