Results 61 to 70 of about 3,216,313 (259)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Fault Tree Analysis for Robust Design
DesignsThe objective of this research is to incorporate system failure into a robust design formation and solution process. The system failure referred to here will be built using fault tree analysis (FTA), which will take all lower-level failure events into ...
Jonathan DeGroff, Gene Jean-Win Hou
doaj +1 more source
Quality engineering of a traction alternator by robust design [PDF]
, 2010 Robust design is an engineering methodology for improving productivity during research and development so that high-quality products can be developed and produced quickly and at low cost. A large electrical company was developing traction alternators for
E V Gijo +14 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
IEEE AccessMost electrical machine design optimization processes do not include constraints imposed during manufacture. Ignoring cutting tolerance when optimizing a machine, for example, can result in a machine who’s performance is susceptible to ...
Farshid Mahmouditabar, Nick J. Baker
doaj +1 more source
Optimal Design of Robust Combinatorial Mechanisms for Substitutable Goods
, 2017 In this paper we consider multidimensional mechanism design problem for selling discrete substitutable items to a group of buyers. Previous work on this problem mostly focus on stochastic description of valuations used by the seller.
A Ben-Tal +10 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Study on Robust Design for Aviation Gear Reducer
Hangkong gongcheng jinzhan, 2018 Aviation gear reducer usually has high requirements for weight, strength, reliability and efficiency. Considering the random characteristic of working conditions, the difference of technological level and the fluctuation of mechanical parameters such as ...
Han Binghai
doaj +1 more source
Tolerance Design and Robust Study for The Joint Clearances of Landing Gear Retraction Mechanisms
Applied Sciences, 2020 Joint clearances inevitably affect the kinematic accuracy and robustness of landing gear retraction mechanisms. However, the complexity and uncertainty of the clearances lead to difficulty in establishing mathematic models and analyzing effects.
Li Zhang, Hong Nie, Xiaohui Wei
doaj +1 more source
Multi-objective design of robust flight control systems [PDF]
, 2008 A multi–objective evolutionary algorithm is used in the framework of H1 control theory to find the controller gains that minimize a weighted combination of the infinite–norm of the sensitivity function (for disturbance attenuation requirements) and ...
Avanzini, G. +3 more
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