Results 51 to 60 of about 1,524,562 (340)

Robust high-dimensional precision matrix estimation

open access: yes, 2015
The dependency structure of multivariate data can be analyzed using the covariance matrix $\Sigma$. In many fields the precision matrix $\Sigma^{-1}$ is even more informative.
B. Bertsekas   +24 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The Impact of Outliers on Net-Benefit Regression Model in Cost-Effectiveness Analysis. [PDF]

open access: yesPLoS ONE, 2013
Ordinary least square (OLS) in regression has been widely used to analyze patient-level data in cost-effectiveness analysis (CEA). However, the estimates, inference and decision making in the economic evaluation based on OLS estimation may be biased by ...
Yu-Wen Wen   +3 more
doaj   +1 more source

Robust Location Estimates

open access: yesThe Annals of Statistics, 1977
Measures of location differentiable at every density in the Hellinger metric are constructed in this paper. Differentiability entitles these location functionals to the label "robust," even though their influence curves need not be bounded and continuous.
openaire   +3 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright   +13 more
wiley   +1 more source

Robust Estimation for Linear Panel Data Models

open access: yes, 2020
In different fields of applications including, but not limited to, behavioral, environmental, medical sciences and econometrics, the use of panel data regression models has become increasingly popular as a general framework for making meaningful ...
Agostinelli C   +11 more
core   +2 more sources

Robust Estimation of the Generalized Loggamma Model. The R Package robustloggamma [PDF]

open access: yes, 2015
robustloggamma is an R package for robust estimation and inference in the generalized loggamma model. We briefly introduce the model, the estimation procedures and the computational algorithms.
Agostinelli, Claudio   +3 more
core   +4 more sources

On the Adversarial Robustness of Multivariate Robust Estimation

open access: yesCoRR, 2019
In this paper, we investigate the adversarial robustness of multivariate $M$-Estimators. In the considered model, after observing the whole dataset, an adversary can modify all data points with the goal of maximizing inference errors. We use adversarial influence function (AIF) to measure the asymptotic rate at which the adversary can change the ...
Erhan Bayraktar, Lifeng Lai
openaire   +2 more sources

A Robust Instrumental-Variables Estimator [PDF]

open access: yesThe Stata Journal: Promoting communications on statistics and Stata, 2012
The classical instrumental-variables estimator is extremely sensitive to the presence of outliers in the sample. This is a concern because outliers can strongly distort the estimated effect of a given regressor on the dependent variable. Although outlier diagnostics exist, they frequently fail to detect atypical observations because they are ...
Desbordes, Rodolphe, Verardi, Vincenzo
openaire   +3 more sources

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