Results 51 to 60 of about 439,420 (307)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A New Robust Partial Least Squares Regression Method Based on a Robust and an Efficient Adaptive Reweighted Estimator of Covariance

open access: yesRevstat Statistical Journal, 2019
Partial Least Squares Regression (PLSR) is a linear regression technique developed as an incomplete or “partial” version of the least squares estimator of regression, applicable when high or perfect multicollinearity is present in the predictor ...
Esra Polat , Suleyman Gunay
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Robust Estimators in Geodetic Networks Based on a New Metaheuristic: Independent Vortices Search

open access: yesSensors, 2019
Geodetic networks provide accurate three-dimensional control points for mapping activities, geoinformation, and infrastructure works. Accurate computation and adjustment are necessary, as all data collection is vulnerable to outliers.
Ismael Érique Koch   +5 more
doaj   +1 more source

On a fast, robust estimator of the mode: Comparisons to other robust estimators with applications

open access: yesComputational Statistics & Data Analysis, 2006
Advances in computing power enable more widespread use of the mode, which is a natural measure of central tendency since, as the most probable value, it is not influenced by the tails in the distribution. The properties of the half-sample mode, which is a simple and fast estimator of the mode of a continuous distribution, are studied.
David R. Bickel, Rudolf Frühwirth
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust estimation in simultaneous equations models [PDF]

open access: yes, 1994
In this paper we review existing work on robust estimation for simultaneous equations models. Then we discuss three strategies for obtaining estimators with a high breakdown point, a controllable efficiency, and a reasonable computational cost: (a ...
Yohai, Víctor J., Maronna, Ricardo A.
core  

Robust state estimation using mixed integer programming

open access: yes, 2008
This letter describes a robust state estimator based on the solution of a mixed integer program. A tolerance range is associated with each measurement and an estimate is chosen to maximize the number of estimated measurements that remain within tolerance
Irving, MR
core   +1 more source

Robust error-state Kalman-type filters for attitude estimation

open access: yesEURASIP Journal on Advances in Signal Processing
State estimation techniques appear in a plethora of engineering fields, in particular for the attitude estimation application of interest in this contribution. A number of filters have been devised for this problem, in particular Kalman-type ones, but in
Andrea Bellés   +4 more
doaj   +1 more source

Joint Event Density and Curvature Within Spatio-Temporal Neighborhoods-Based Event Camera Noise Reduction and Pose Estimation Method for Underground Coal Mine

open access: yesMathematics
Aiming at the problems of poor image quality of traditional cameras and serious noise interference of event cameras under complex lighting conditions in coal mines, an event denoising algorithm fusing spatio-temporal information and a method of denoising
Wenjuan Yang   +6 more
doaj   +1 more source

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