Results 81 to 90 of about 1,494,076 (289)
Efficient and robust estimation for financial returns: an approach based on q-entropy [PDF]
We consider a new robust parametric estimation procedure, which minimizes an empirical version of the Havrda-Charv_at-Tsallis entropy. The resulting estimator adapts according to the discrepancy between the data and the assumed model by tuning a single ...
Davide Ferrari, Sandra Paterlini
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
ROBUSTNESS OF PRODUCTIVITY ESTIMATES* [PDF]
The Journal of Industrial Economics, 2007 Researchers interested in estimating productivity can choose from an array of methodologies, each with its strengths and weaknesses. We compare the robustness of five widely used techniques, two non‐parametric and three parametric: in order, (a) index numbers, (b) data envelopment analysis (DEA), (c) stochastic frontiers, (d) instrumental variables ...
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Annals of Mathematical Statistics, 1969 Abstract : The problem of finding robust estimators for the location parameter of symmetric unimodal distributions has been the subject of much recent research. This paper is concerned with finding robust estimators which are linear functions of the ordered observations.
Gastwirth, Joseph L., Rubin, Herman
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Australian & New Zealand Journal of StatisticsSummaryRobust estimation is primarily concerned with providing reliable parameter estimates in the presence of outliers. Numerous robust loss functions have been proposed in regression and classification, along with various computing algorithms.
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Robust Confidence Intervals for PM2.5 Concentration Measurements in the Ecuadorian Park La Carolina
Sensors, 2020 In this article, robust confidence intervals for PM2.5 (particles with size less than or equal to 2.5 μ m ) concentration measurements performed in La Carolina Park, Quito, Ecuador, have been built.
Wilmar Hernandez +3 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source