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Robust machine learning methods.
, 2022 We are surrounded by data in our daily lives. The rent of our houses, the amount of electricity units consumed, the prices of different products at a supermarket, the daily temperature, our medicine prescriptions, our internet search history are all different forms of data. Data can be used in a wide range of applications. For example, one can use data
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Characterization and Mapping of retr04, retr05 and retr06 Broad-Spectrum Resistances to Turnip Mosaic Virus in Brassica juncea, and the Development of Robust Methods for Utilizing Recalcitrant Genotyping Data. [PDF]
Front Plant Sci, 2021 Bramham LE +5 more
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Applied SciencesControlling for confounding bias is crucial in causal inference. Causal inference using data from observational studies (e.g., electronic health records) or imperfectly randomized trials (e.g., imperfect randomization or compliance) requires accounting ...
Amy X. Shi, Paul N. Zivich, Haitao Chu
doaj +1 more source
A Robust Remote Photoplethysmography Method
CoRRRemote photoplethysmography (rPPG) is a method for measuring a subjects heart rate remotely using a camera. Factors such as subject movement, ambient light level, makeup etc. complicate such measurements by distorting the observed pulse. Recent works on this topic have proposed a variety of approaches for accurately measuring heart rate in humans ...
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Nonparametric and Robust Methods
Computational Statistics & Data Analysis, 2007 Rand R. Wilcox +3 more
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