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The Construction of Efficient Portfolios: A Verification of Risk Models for Investment Making
Frontiers in Applied Mathematics and Statistics, 2020 Various statistical models have been used in estimating inputs to mean-variance efficient portfolio construction since the mid-1960s. One can argue how many factors are necessary, but there appears to be substantial evidence that statistical models ...
Mustafa N. Gültekin +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Annals of Statistics, 1987 Let \(y_ t=x'_ t\beta +u_ t\), \(t\in Z^ 1\), where the disturbances \(u_ t\) follow a second-order stationary process with E \(u_ t=0\). The spectral density f(\(\lambda)\) of a process \(u_ t\) is unknown but belongs to a neighborhood of some special spectral density \(f_ 0(\lambda)\).
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Venture Capital and Private Equity Diversification: A Var and DCC Garch Approach
Корпоративные финансыThe terms “venture capital” and “private equity” are used in a loosely interchangeable manner when capital is invested in innovative technology-driven ideas or nascent-stage/unlisted companies.
Manu Sharma
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The impact of politics on fiscal behavior: the case of Brazil
Economia Aplicada, 2006 This paper examines the proposition that a government which faces an election or depends on general popular support to govern effectively will find it difficult to resist increasing expenditures or to raise taxes.
Werner Baer, Donald V. Coes
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Robust Kibria Estimators for Mitigating Multicollinearity and Outliers in a Linear Regression Model
StatsIn the presence of multicollinearity, the ordinary least squares (OLS) estimators, aside from BLUE (best linear unbiased estimator), lose efficiency and fail to achieve minimum variance.
Hina Naz +3 more
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Robust Statistical Approaches for RSS-Based Floor Detection in Indoor Localization
Sensors, 2016 Floor detection for indoor 3D localization of mobile devices is currently an important challenge in the wireless world. Many approaches currently exist, but usually the robustness of such approaches is not addressed or investigated.
Alireza Razavi +2 more
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