Results 41 to 50 of about 624,142 (260)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Robust Segmentation of Planar and Linear Features of Terrestrial Laser Scanner Point Clouds Acquired from Construction Sites

Sensors, 2018
Automated segmentation of planar and linear features of point clouds acquired from construction sites is essential for the automatic extraction of building construction elements such as columns, beams and slabs.
Reza Maalek, Derek D Lichti, Janaka Y Ruwanpura   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

FORCE: Fast Outlier-Robust Correlation Estimation via Streaming Quantile Approximation for High-Dimensional Data Streams

Mathematics
The estimation of correlation matrices in high-dimensional data streams presents a fundamental conflict between computational efficiency and statistical robustness.
Sooyoung Jang, Changbeom Choi
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Lower Bounds for the Asymptotic Relative Efficiency of Huber Regression

Mathematics
Huber regression serves as a prominent robust alternative to ordinary least squares (OLS), particularly in the presence of heavy-tailed error distributions.
Xiaoyi Wang, Le Zhou
doaj   +1 more source

Analysis of ‘Pre-Fit’ Datasets of gLAB by Robust Statistical Techniques

Stats, 2021
The GNSS LABoratory tool (gLAB) is an interactive educational suite of applications for processing data from the Global Navigation Satellite System (GNSS).
Maria Teresa Alonso, Carlo Ferigato, Deimos Ibanez Segura, Domenico Perrotta, Adria Rovira-Garcia, Emmanuele Sordini   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

DSFNet: A Directional Statistical Fusion Network for Cloud and Cloud Shadow Segmentation

Remote Sensing
Accurate cloud and cloud shadow segmentation is a critical prerequisite for remote sensing image preprocessing. However, this task remains challenging due to the directional continuity of projected cloud shadows, the radiometric ambiguity between low ...
Yuqi Fang, Zhiyong Fan, Min Xia, Ni Li, Xiaolin Yang   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source