Results 111 to 120 of about 2,324,507 (326)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
SWEEPFINDER2: Increased sensitivity, robustness, and flexibility
, 2015 SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael +4 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Realization of AlSb in the Double-Layer Honeycomb Structure: A Robust Class of Two-Dimensional Material [PDF]
, 2021 Le Qin +12 more
openalex +1 more source
Residual effect on the robustness of multiqubit entanglement
, 2010 We investigate the relation between the entanglement and the robustness of a multipartite system to a depolarization noise. We find that the robustness of a two-qubit system in an arbitrary pure state depends completely on its entanglement. However, this
Deng, Fu-Guo, Zhao, Bao-Kui
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Electropolymerization of robust conjugated microporous polymer membranes for rapid solvent transport and narrow molecular sieving [PDF]
, 2020 Zongyao Zhou +10 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Transparent communication of robustness is essential in empirical research, yet existing toolscan be difficult to interpret. This paper introduces the robustness dashboard, a graphical tool thatvisualizes the results of robustness reproductions into a single, intuitive graph.
Gunther Bensch +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source