Results 91 to 100 of about 1,259,858 (300)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Selecting the Best Quantity and Variety of Surrogates for an Ensemble Model

open access: yesMathematics, 2020
Surrogate modeling techniques are widely used to replace the computationally expensive black-box functions in engineering. As a combination of individual surrogate models, an ensemble of surrogates is preferred due to its strong robustness.
Pengcheng Ye, Guang Pan
doaj   +1 more source

Robustness-Driven Resilience Evaluation of Self-Adaptive Software Systems [PDF]

open access: yes, 2015
An increasingly important requirement for certain classes of software-intensive systems is the ability to self-adapt their structure and behavior at run-time when reacting to changes that may occur to the system, its environment, or its goals.
de Lemos, Rogerio   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Distributed robust RLS estimation algorithm over sensor networks

open access: yesDianxin kexue, 2019
In the parameter estimation of the sensor network, there may be impact noise or pulse interference in the measurement environment, which leads to the outliers that greatly deviate from the actual range, so that the effective parameter estimation problem ...
Kaikai KANG, Zhaoting LIU, Yingbiao YAO
doaj  

Cognitive Bias-Inspired Deep Robust Neural Networks Against Transfer-Based Attacks Considering Confidence Score

open access: yesVietnam Journal of Computer Science
Transfer-based attacks, a type of adversarial attack, have become a growing threat in recent years with the proliferation of cloud services. Deep neural networks that exploit human cognitive bias (Loosely Symmetric-Deep Neural Network, LS-DNN) are known ...
Yuuki Ogasawara   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Robust digital watermark method based on PDF417 two-dimension code

open access: yes网络与信息安全学报, 2016
A digital watermark method based on the bar-block-margin characteristics of PDF417 two-dimension code was presented.The proposed method prejudges the watermark information to choose the suitable embedding positions.According to the watermark,the ...
Cui-ling JIANG   +5 more
doaj  

Specifying Robustness

open access: yesCoRR, 2013
This paper proposes a new logic RoCTL* to model robustness in concurrent systems. RoCTL* extends CTL* with the addition of Obligatory and Robustly operators, which quantify over failure-free paths and paths with one more failure respectively. We present a number of examples of problems to which RoCTL* can be applied. The core result of this paper is to
John Christopher McCabe-Dansted   +3 more
openaire   +2 more sources

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