Results 71 to 80 of about 698,739 (268)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Analytical performance of an inductively coupled plasma optical emission spectrometry with Dual View configuration

open access: yesJournal of the Brazilian Chemical Society, 2003
The analytical performance of axially and radially viewed inductively coupled plasma optical emission spectrometers (AX-ICP OES and RD-ICP OES, respectively) were evaluated in terms of the Mg II/Mg I ratio, matrix effects, and detection limits (LOD). All
Silva Júlio C. J.   +2 more
doaj  

Research of PMSM-DTC system based on the super-twisting second sliding mode control

open access: yesJournal of Hebei University of Science and Technology, 2017
Aiming at the problems that the conventional permanent magnet synchronous motor direct torque control system (PMSM-DTC) is susceptible to the influence of parameter change and torque ripple, it is proposed that the space voltage vector modulation ...
Suying ZHANG   +4 more
doaj   +1 more source

Robustness during Aging—Molecular Biological and Physiological Aspects

open access: yesCells, 2020
Understanding the process of aging is still an important challenge to enable healthy aging and to prevent age-related diseases. Most studies in age research investigate the decline in organ functionality and gene activity with age.
Emanuel Barth   +3 more
doaj   +1 more source

Robust artificial intelligence and robust human organizations [PDF]

open access: yesFrontiers of Computer Science, 2018
Every AI system is deployed by a human organization. In high risk applications, the combined human plus AI system must function as a high-reliability organization in order to avoid catastrophic errors. This short note reviews the properties of high-reliability organizations and draws implications for the development of AI technology and the safe ...
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Accuracy Assessment of Small Unmanned Aerial Vehicle for Traffic Accident Photogrammetry in the Extreme Operating Conditions of Kuwait

open access: yesInformation, 2020
This study presents the first accuracy assessment of a low cost small unmanned aerial vehicle (sUAV) in reconstructing three dimensional (3D) models of traffic accidents at extreme operating environments.
Abdullah M. Almeshal   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Selecting the Best Quantity and Variety of Surrogates for an Ensemble Model

open access: yesMathematics, 2020
Surrogate modeling techniques are widely used to replace the computationally expensive black-box functions in engineering. As a combination of individual surrogate models, an ensemble of surrogates is preferred due to its strong robustness.
Pengcheng Ye, Guang Pan
doaj   +1 more source

Pareto adversarial robustness: balancing spatial robustness and sensitivity-based robustness

open access: yesScience China Information Sciences
Adversarial robustness, which primarily comprises sensitivity-based robustness and spatial robustness, plays an integral part in achieving robust generalization. In this paper, we endeavor to design strategies to achieve universal adversarial robustness.
Ke Sun 0013   +2 more
openaire   +2 more sources

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