Results 51 to 60 of about 698,739 (268)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Experimental Validation of a Novel Auto-Tuning Method for a Fractional Order PI Controller on an UR10 Robot

open access: yesAlgorithms, 2018
Classical fractional order controller tuning techniques usually consider the frequency domain specifications (phase margin, gain crossover frequency, iso-damping) and are based on knowledge of a process model, as well as solving a system of nonlinear ...
Cristina I. Muresan   +5 more
doaj   +1 more source

Interactive Planning of Competency-Driven University Teaching Staff Allocation

open access: yesApplied Sciences, 2020
This paper focuses on a teacher allocation problem that is specifically concerned with assigning available academic lecturers to remaining courses from a given student curriculum.
Eryk Szwarc   +4 more
doaj   +1 more source

Robust Learning with Noisy Ship Trajectories by Adaptive Noise Rate Estimation

open access: yesSensors, 2023
Ship trajectory classification is of great significance for shipping analysis and marine security governance. However, in order to cover up their illegal fishing or espionage activities, some illicit ships will forge the ship type information in the ...
Haoyu Yang   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dynamics of Systems with a Discontinuous Hysteresis Operator and Interval Translation Maps

open access: yesAxioms, 2021
We studied topological and metric properties of the so-called interval translation maps (ITMs). For these maps, we introduced the maximal invariant measure and study its properties. Further, we study how the invariant measures depend on the parameters of
Sergey Kryzhevich   +4 more
doaj   +1 more source

Robust Robustness

open access: yes
We propose a refinement of the maxmin approach to robustness. A mechanism's payoff guarantee over an ambiguity set is \emph{robust} if the guarantee is approximately satisfied at priors near the ambiguity set (in the weak topology). We show that many maxmin-optimal mechanisms in the literature give payoff guarantees that are not robust. Such mechanisms
Ball, Ian, Kattwinkel, Deniz
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Transparent and Robust All-Cellulose Nanocomposite Packaging Materials Prepared in a Mixture of Trifluoroacetic Acid and Trifluoroacetic Anhydride

open access: yesNanomaterials, 2019
All-cellulose composites with a potential application as food packaging films were prepared by dissolving microcrystalline cellulose in a mixture of trifluoroacetic acid and trifluoroacetic anhydride, adding cellulose nanofibers, and evaporating the ...
Susana Guzman-Puyol   +7 more
doaj   +1 more source

Antifragility Predicts the Robustness and Evolvability of Biological Networks through Multi-Class Classification with a Convolutional Neural Network

open access: yesEntropy, 2020
Robustness and evolvability are essential properties to the evolution of biological networks. To determine if a biological network is robust and/or evolvable, it is required to compare its functions before and after mutations.
Hyobin Kim   +3 more
doaj   +1 more source

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