Results 131 to 140 of about 562,963 (309)

Ethanol Drives Evolution of Hsp90-Dependent Robustness by Redundancy in Yeast Domestication [PDF]

, 2023
Dipak Patel, Hatim Amiji, William C. Shropshire, Natalia Condic, Nejla Ozirmak Lermi, Youssef Sabha, B. Greenly John, Blake Hanson, Georgios Ioannis Karras   +8 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Constraint propagation ofC2-adjusted formulation: Another recipe for robust ADM evolution system [PDF]

, 2011
Takuya Tsuchiya, Gen Yoneda, H. Shinkai
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Evolution of a high-performance and functionally robust musculoskeletal system in salamanders

, 2020
Stephen M. Deban, Jeffrey A. Scales, Segall V. Bloom, Charlotte M. Easterling, Mary Kate O’Donnell, Jeffrey P. Olberding   +5 more
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PolyCRACKER, a robust method for the unsupervised partitioning of polyploid subgenomes by signatures of repetitive DNA evolution [PDF]

, 2018
Sean Gordon, Joshua Levy, John P. Vogel
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Somatic evolution of head and neck cancer — Biological robustness and latent vulnerability [PDF]

, 2012
Muneyuki Masuda, Satoshi Toh, Takahiro Wakasaki, Masumi Suzui, Andrew K. Joe   +4 more
openalex   +1 more source

Observation of a robust and active catalyst for hydrogen evolution under high current densities [PDF]

, 2022
Yudi Zhang, Kathryn E. Arpino, Qun Yang, Naoki Kikugawa, D. A. Sokolov, Clifford W. Hicks, Jian Liu, Claudia Felser, Guowei Li   +8 more
openalex   +1 more source