Results 191 to 200 of about 99,185 (278)

The evolution of robustness and fragility during long-term bacterial adaptation. [PDF]

Proc Natl Acad Sci U S A
Chihoub D, Pintard C, Lenski RE, Tenaillon O, Couce A.   +4 more
europepmc   +1 more source

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan, Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer, Jesse A. Brown, Alex J. Lee, Kristen Fernhoff, Lorenzo Pasquini, Katherine P. Rankin, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Tatiana Foroud, Daniel H. Geschwind, Nupur Ghoshal, Neill R. Graff‐Radford, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward Huey, Kejal Kantarci, Irene Litvan, Ian R. Mackenzie, Mario F. Mendez, Chiadi U. Onyike, Leonard Petrucelli, Eliana Marisa Ramos, Erik D. Roberson, Julio C. Rojas, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Leah K. Forsberg, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, Fermin Moreno, William W. Seeley, Suzee E. Lee, on behalf of the ALLFTD Consortium   +46 more
wiley   +1 more source

Optimization of machine tool processing scheduling based on differential evolution algorithm. [PDF]

PLoS One
Zhang Y, Zhang M.
europepmc   +1 more source

ARCANE-ROG: Algorithm for reconstruction of cancer evolution from single-cell data using robust graph learning

, 2022
Akanksha Farswan, Ritu Gupta, Anubha Gupta   +2 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Current status and solutions for AI ethics in ophthalmology: a bibliometric analysis. [PDF]

NPJ Digit Med
Chen X, Yang Y, Yun D, Wang R, Lin Y, Luo M, Zhang W, Yu-Wai-Man P, Burton M, Liang L, Lin H.   +10 more
europepmc   +1 more source

Coupling of ultrasmall and small Co P nanoparticles confined in porous SiO2 matrix for a robust oxygen evolution reaction

, 2022
Xiaojun Zeng, Haiqi Zhang, Xiaofeng Zhang, Qingqing Zhang, Yunxia Chen, Ronghai Yu, Martin Moskovits   +6 more
openalex   +1 more source

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

High-fidelity geometric quantum gates exceeding 99.9% in germanium quantum dots. [PDF]

Nat Commun
Zhou YC, Ma RL, Kong Z, Li AR, Zhang C, Zhang X, Liu Y, Jiang HT, Wu ZT, Wang GL, Cao G, Guo GC, Li HO, Guo GP.   +13 more
europepmc   +1 more source

Empirical analysis of RNA robustness and evolution using high-throughput sequencing of ribozyme reactions

, 2016
Eric J. Hayden
openalex   +2 more sources