Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu+11 more
wiley +1 more source
Visual function changes of dysthyroid optic neuropathy and ROC curve analysis for early diagnostic indicators. [PDF]
Wang S, Wang J, Chen L, Tan J.
europepmc +1 more source
Nonparametric Estimation of ROC Curves in the Absence of a Gold Standard
Xiao‐Hua Zhou+2 more
openalex +2 more sources
Diagnostic methods 2: receiver operating characteristic (ROC) curves [PDF]
Giovanni Tripepi+3 more
openalex +1 more source
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang+14 more
wiley +1 more source
Evaluating the Efficacy of Longitudinal Coagulation Biomarkers to Predict in-Hospital Death in Comatose TBI Patients: A Time-Dependent Roc Curve Approach. [PDF]
Ebrahimi-Nejad F+5 more
europepmc +1 more source
Cardiorespiratory Fitness Predicted by Fibrinogen and Leptin Concentrations in Children with Obesity and Risk for Diabetes: A Cross-Sectional Study and a ROC Curve Analysis. [PDF]
Tsiroukidou K+7 more
europepmc +1 more source
Estimation of the ROC Curve under Verification Bias [PDF]
Ronen Fluss+3 more
openalex +1 more source
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding+16 more
wiley +1 more source
A unified Bayesian framework for exact inference of area under the receiver operating characteristic curve. [PDF]
Lin R, Chan KG, Shi H.
europepmc +1 more source