Results 171 to 180 of about 302,402 (283)

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

open access: yesAdvanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu   +11 more
wiley   +1 more source

Visual function changes of dysthyroid optic neuropathy and ROC curve analysis for early diagnostic indicators. [PDF]

open access: yesZhong Nan Da Xue Xue Bao Yi Xue Ban, 2023
Wang S, Wang J, Chen L, Tan J.
europepmc   +1 more source

Diagnostic methods 2: receiver operating characteristic (ROC) curves [PDF]

open access: bronze, 2009
Giovanni Tripepi   +3 more
openalex   +1 more source

Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis

open access: yesAdvanced Science, EarlyView.
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang   +14 more
wiley   +1 more source

Estimation of the ROC Curve under Verification Bias [PDF]

open access: green, 2009
Ronen Fluss   +3 more
openalex   +1 more source

ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metastasis by Regulating the PALLD‐Mediated EMT Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding   +16 more
wiley   +1 more source

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