Results 51 to 60 of about 2,344,066 (336)

Monitoring Livestock Health by Modeling Rumination Behavior According to Accelerometer-Based Information [PDF]

open access: yesJournal of Agricultural Machinery
IntroductionThe livestock sector excels in the production of dairy and meat products. These products, serving as vital sources of animal protein, hold a significant position in household diets.
E. Vahedi Tekmehdash   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Diagnosis: shifting the ROC curve [PDF]

open access: yesBritish Journal of General Practice, 2012
In 1972 Howie asked whether diagnosis was the Achilles heel of general practice.1 Accurate diagnosis was then, and remains, the fundamental concept of all medical practice. Are we any good at it now? This issue of the BJGP contains several papers on diagnosis and decision-making which shed light on this important area of practice. The results reported
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

A boosting method for maximizing the partial area under the ROC curve

open access: yesBMC Bioinformatics, 2010
Background The receiver operating characteristic (ROC) curve is a fundamental tool to assess the discriminant performance for not only a single marker but also a score function combining multiple markers.
Eguchi Shinto, Komori Osamu
doaj   +1 more source

ROCS: receiver operating characteristic surface for class-skewed high-throughput data. [PDF]

open access: yesPLoS ONE, 2012
The receiver operating characteristic (ROC) curve is an important tool to gauge the performance of classifiers. In certain situations of high-throughput data analysis, the data is heavily class-skewed, i.e.
Tianwei Yu
doaj   +1 more source

Lehmann Family of ROC Curves

open access: yesMedical Decision Making, 2010
Receiver operating characteristic (ROC) curves evaluate the discriminatory power of a continuous marker to predict a binary outcome. The most popular parametric model for an ROC curve is the binormal model, which assumes that the marker, after a monotone transformation, is normally distributed conditional on the outcome.
Mithat, Gönen, Glenn, Heller
openaire   +3 more sources

nsROC: An R package for Non-Standard ROC Curve Analysis

open access: yesThe R Journal, 2018
The receiver operating characteristic (ROC) curve is a graphical method which has become standard in the analysis of diagnostic markers, that is, in the study of the classification ability of a numerical variable.
Sonia Pérez-Fernández   +3 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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