Results 81 to 90 of about 2,919,066 (271)

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Covariate Adjusted ROC Curve Analysis and An Application

open access: yesSakarya Tıp Dergisi, 2015
Objective: Aim of this study is to analyze the change of the area under the adjusted ROC (AdjROC) curve in certain conditions via binormal distribution model using simulation studies and application of this algorithm to real data.
Cengiz Bal   +5 more
doaj  

Comparative assessment of three common algorithms for estimating the variance of the area under the nonparametric receiver operating characteristic curve [PDF]

open access: yes
The area under the receiver operating characteristic (ROC) curve is often used to summarize and compare the discriminatory accuracy of a diagnostic test or modality,and to evaluate the predictive power of statistical models for binary outcomes ...
Mario A. Cleves
core   +1 more source

Cumulative/dynamic ROC curve estimation

open access: yes, 2016
Receiver operating-characteristic (ROC) curve is a popular graphical method frequently used in order to study the diagnostic capacity of continuous (bio)markers. When the considered outcome is a time-dependent variable, the direct generalization is known
P. Martínez-Camblor   +2 more
semanticscholar   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

Determination of ROC Curve based diagnostic strength of miRNA in ovarian cancer

open access: yesJournal of the Pakistan Medical Association
Objective: To examine the diagnostic accuracy of 10 serum-derived micro ribonucleic acids in the early detection of ovarian cancer. Method: The cross-sectional, comparative study was conducted at the Department of Physiology and Cell Biology ...
Rizwana Hussain, Saba Khaliq
doaj   +1 more source

On the Binormal Predictive Receiver Operating Characteristic Curve for the Joint Assessment of Positive and Negative Predictive Values

open access: yesEntropy, 2020
The predictive receiver operating characteristic (PROC) curve is a diagrammatic format with application in the statistical evaluation of probabilistic disease forecasts.
Gareth Hughes
doaj   +1 more source

An Improved Method for Bandwidth Selection when Estimating ROC Curves [PDF]

open access: yes
The receiver operating characteristic (ROC) curve is used to describe the performance of a diagnostic test which classifies observations into two groups.
Peter Hall, Rob J. Hyndman
core  

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

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