Results 121 to 130 of about 140,547 (299)

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

A Study on the Effects of Hob Temperature on the Rock-Breaking Characteristics of Sandstone Strata

Applied Sciences
To explore the effect of hob temperature on the rock-breaking characteristics of full-section tunnel boring machines (TBMs) in sandstone strata, high-temperature furnace heating experiments of sandstone and physical and mechanical experiments at room ...
Yun-Gui Pan, You-Liang Chen, Xi Du, Hui-Dong Tong, Fei-Yu Tang, Xiao-Jian Wu, Su-Ran Wang, Shao-Ming Liao, Bin Peng   +8 more
doaj   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Multifunctional Tailoring of Fertilizer Composites Directly Derived From Phosphate Rock

Advanced Science, EarlyView.
A novel phosphorus‑sulfur mixed acid with urea (PSU) activation system converts low‑grade phosphate rock (LPR) into multifunctional fertilizer composites (MFCs). MFCs feature porous structures, high nutrient‑activation efficiency, superior slow‑release, and enhanced crop growth, offering a sustainable solution for integrated nutrient management and ...
Zenglian Qi, Jianchao Wang, Lulu Chen, Zhenya Lu, Guodong Wang, Hang Ma, Cuihong Hou, Xinxin Wang, Wenqi Ma, Changzhou Wei, Jianbo Shen, Fusuo Zhang, Minghao Zhuang, Chengdong Huang   +13 more
wiley   +1 more source

Characterization of Dolomite Stone Broken Under Axial Impact

Applied Sciences
As the extraction of oil and gas progresses into deeper and ultra-deep geological formations, the enhancement of rock-breaking efficiency in drill bits has emerged as a critical factor in ensuring energy security.
Ran Ji, Han Chen, Huaizhong Shi, Wenhao He, Dong Liu, Yongqi Wang   +5 more
doaj   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

The Influence Mechanism of Conical Pick Wear on Rock Breaking Efficiency Based on Indentation Tests

Eng
With the deepening of mineral resource exploitation, conical picks are subjected to severe wear under high-stress and high-friction conditions, which has become a critical factor governing rock-breaking efficiency.
Yunfei Xia, Youlu Yuan, Hongchao Wang, Lei Lyu   +3 more
doaj   +1 more source

Nuclearite search with the MACRO detector at Gran Sasso

, 1999
In this paper we present the results of a search for nuclearites in the penetrating cosmic radiation using the scintillator and track-etch subdetectors of the MACRO apparatus. The analyses cover the beta =v/c range at the detector depth (3700 hg/cm^2) 10^
Ambrosio M, Antolini R, Aramo C, Auriemma G, Baldini A, Barbarino GC, Barish BC, Battistoni G, Bellotti R, Bemporad C, Bernardini P, Bilokon H, Bisi V, Bloise C, Bower C, Bussino S, Cafagna F, Calicchio M, Campana D, Carboni M, Castellano M, Cecchini S, Cei F, Chiarella V, Choudhary BC, Coutu S, De Benedictis L, De Cataldo G, De Marzo E, De Mitri I, De Vincenzi M, Dekhissi H, Derkaoui J, Di Credico A, Erriquez O, Favuzzi C, Forti C, Fusco P, Giacomelli G, Giannini G, Giglietto N, Giorgini M, Grassi M, Gray L, Grillo A, Guarino F, Guarnaccia P, Gustavino C, Habig A, Hanson K, Heinz R, Huang Y, Iarocci E, Katsavounidis E, Kearns E, Kim H, Kyriazopoulou S, Lamanna E, Lane C, Lari T, Levin DS, Lipari P, Longley NP, Longo MJ, Maaroufi F, Mancarella G, Mandrioli G, Manzoor S, Margiotta A, Marini A, Martello D, Marzari-Chiesa A, Mazziotta MN, Michael DG, Mikheyev S, Miller L, Monacelli P, Montaruli T, Monteno M, Mufson S, Musser J, Nicolo D, Orth C, Osteria G, Ouchrif M, Palamara O, Patera V, Patrizii L, Pazzi R, Peck CW, Perrone L, Petrera S, Pistilli P, Popa V, Pugliese V, Raino A, Rastelli A, Reynoldson J, Ronga F, Rubizzo U, Satriano C, Satta L, Scapparone E, Scholberg K, Sciubba A, Serra P, Severi M, Sioli M, Sitta M, Spinelli P, Spinetti M, Spurio M, Steinberg R, Stone JL, Sulak LR, Surdo A, Tarle G, Togo V, Ugolotti D, Vakili M, Walter CW, Webb R   +121 more
core   +1 more source

Free‐Volume Regulation Enables Significantly Enhanced Electrical Breakdown via Short‐Chain Molecular Spatial‐Positioning Intercalation into Poly(vinylidene fluoride)

Advanced Science, EarlyView.
An innovative molecular spatial‐positioning shimming strategy is developed to optimize the electrical properties of poly(vinylidene fluoride) (PVDF). By intercalating polyethylene wax (PE wax) short‐chain molecules into PVDF's free volume, the film achieves a significantly enhanced energy density of 32.67 J cm−3.
Ziyue Wang, Jiyang Xie, Wanbiao Hu
wiley   +1 more source