Results 121 to 130 of about 140,868 (311)

Boosting Photo‐Pyroelectric Effect via Tunable Polarization and Interfacial Defect Engineering

open access: yesAdvanced Science, EarlyView.
This study reports Ba(Ti0.85Zr0.15)O3 nanocatalysts with enhanced polarization and oxygen‐vacancy‐rich interfaces for efficient NIR‐II photo‐pyroelectric therapy. Zr doping boosts the pyroelectric coefficient and accelerates polarization switching, while oxygen vacancies improve photothermal conversion and surface reactivity.
Yanli Huang   +13 more
wiley   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

open access: yesAdvanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma   +10 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Research Progress and Prospect on Laser Drilling Technology

open access: yesShiyou jixie, 2016
The conventional rotary drilling usually leads to drilling tool wear, which results in frequent drill bit replacement, causing long drilling period and high cost.The laser drilling technology could greatly improve the drilling speed and shorten the ...
Zhang Shiyi   +4 more
doaj  

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

open access: yesAdvanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou   +19 more
wiley   +1 more source

New Tehniques of Pressure Relief and Permeability Enhancement by Abrasive Jet in Coal Mine Roadways

open access: yesShiyou jixie, 2023
Pure water jet penetration in hard coal seams is deficient for low rock-breaking efficiency and complex operation.This paper presents two new techniques of pressure relief and permeability enhancement by deep penetration with abrasive jet and by radial ...
Wang Bin   +6 more
doaj  

Deconstructing Corporate Governance: Director Primacy Without Principle? [PDF]

open access: yes, 2011
For almost eighty years now, corporate law scholarship has centered around two elementary analytical findings made in what has once been described as the “last major work of original scholarship”within the ...
Reich-Graefe, René
core   +2 more sources

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang   +11 more
wiley   +1 more source

Numerical simulation of optimal jet angle of water jet assisted disc cutter rock breaking

open access: yesMeitan kexue jishu
In order to solve the problems of difficulty in tunneling, serious tool loss and low efficiency of breaking ultra-high strength rock encountered in the construction process of traditional hob, high-pressure water jet has become a new method to improve ...
Anxin WANG   +5 more
doaj   +1 more source

Rock Breaking Mechanisms and Heat Generation Analysis on High Temperature Rocks in Deep Wells

open access: yesShiyou jixie, 2021
In order to improve the rock breaking efficiency of PDC cutter in high temperature formations in deep wells, granite and sandstone are heated respectively to different temperatures to simulate the high temperature rocks at the deep bottom hole.
Chen Hao   +5 more
doaj  

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