Results 111 to 120 of about 7,673 (292)

#RACItUp: Rock Climbing [PDF]

open access: yes, 2017
Our RAC reporters give you an inside scoop on the Rock Climbing area at the ...
Georgia Southern University, Student Media
core  

Rock climbing as experiential pedagogy in outdoor education: The positive psychology outcomes and students' well-being

open access: yesActa Psychologica
Purpose: This study investigates the pedagogical value of rock climbing in Chinese higher education through the dual lenses of constructivist learning theory and the PERMA+IT framework of positive psychology in outdoor higher education studies.
Jinsheng (Jason) Zhu, Qideng Mo
doaj   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

open access: yesAdvanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng   +17 more
wiley   +1 more source

Sex Differences in Children's Motivation and Action Patterns for Climbing as Behavioral Relicts of Ancestral Sexual-Size Dimorphism

open access: yesEvolutionary Psychology
Four studies investigated sex differences in children's motivation and action patterns for climbing playground structures and a gymnasium rock wall to assess any influence of ancestral sexual-size dimorphism limiting tree-climbing agility.
Richard G. Coss   +2 more
doaj   +1 more source

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

open access: yesAdvanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu   +16 more
wiley   +1 more source

ALEXANDER PIRATINSKY – A LEADING SPECIALIST IN ROCK CLIMBING IN RUSSIA AND THE WORLD

open access: yesФизическая культура. Спорт. Туризм. Двигательная рекреация, 2020
A. E. Piratinsky is one of the leading experts in Russia and the world on the theory, methods of training athletes and organizing sports events in rock climbing of the highest rank.
Lyudmila Vladimirovna Moiseeva
doaj  

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

open access: yesAdvanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang   +10 more
wiley   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

open access: yesAdvanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng   +18 more
wiley   +1 more source

Testing of rock climbing anchors [PDF]

open access: yes, 2006
The testing procedures for small rock anchors for various recreational activities including rock climbing are regulated in the European Standard EN959.
Pircher, Martin
core  

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

open access: yesAdvanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal   +9 more
wiley   +1 more source

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