Results 121 to 130 of about 7,673 (292)

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Rock wall climbing [PDF]

, 2000
Rock wall climbing at the Welcome Back BBQ at the University College of the Cariboo Kamloops ...

core  

Uncover rock-climbing fish's secret of balancing tight adhesion and fast sliding for bioinspired robots. [PDF]

Natl Sci Rev, 2023
Tan W, Zhang C, Wang R, Fu Y, Chen Q, Yang Y, Wang W, Zhang M, Xi N, Liu L.   +9 more
europepmc   +1 more source

The craft of rock climbing: exploring the implications of relational ontologies for learning to rock climb

Journal of Outdoor and Environmental Education
AbstractThis paper explores how relational ontologies challenge the conception of skill development in rock climbing. Using especially the concepts of Tim Ingold and Phil Mullins, the paper suggests that pro-environmental behaviours, and relationships to place, can be fostered by direct involvement in skills development.
Peter Hubbard, Colin Wood
openaire   +1 more source

3D‐Printed Magnetoelectronics for Interactive Appliances and Self‐Aware 4D‐Printed Mechatronics

Advanced Science, EarlyView.
3D‐printed magnetoelectronics integrate high‐performance magnetic field sensing directly into complex structural components. Flexible spring and cross‐shaped sensors exhibit giant magnetoimpedance and 3D Hall sensing for vector field reconstruction. Applications include smart‐home switches, robotic joysticks, volumetric magnetometers, and self‐aware 4D‐
Eduardo Sergio Oliveros‐Mata, Anna Martin Vilardell, Fabian Ganss, Christoph Leyens, Lukas Stepien, Denys Makarov   +5 more
wiley   +1 more source

Ted Major rock climbing in Bells Canyon, 1936 [PDF]

, 1936
Black and white photo showing Ted Major rock climbing outing in Bells Canyon in ...

core  

Wearable and Non-Invasive Sensors for Rock Climbing Applications: Science-Based Training and Performance Optimization. [PDF]

Sensors (Basel), 2023
Breen M, Reed T, Nishitani Y, Jones M, Breen HM, Breen MS.   +5 more
europepmc   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Ted Major rock climbing in Bells Canyon, 1936 (Negative) [PDF]

, 1936
Negative of photo showing Ted Major rock climbing outing in Bells Canyon ...

core  

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

Advanced Science, EarlyView.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie, Mengyan Zhu, Zhongxian Zhu, Jiaqi Tang, Ruyi Zhang, Zequan Ding, Junzhi Li, Zhongluan Wu, Paul Kwong Hang Tam, Qianghu Wang, Vincent Chi Hang Lui, Yankai Xia, Weibing Tang   +12 more
wiley   +1 more source