Results 121 to 130 of about 124,943 (294)

Rock climbing as experiential pedagogy in outdoor education: The positive psychology outcomes and students' well-being

open access: yesActa Psychologica
Purpose: This study investigates the pedagogical value of rock climbing in Chinese higher education through the dual lenses of constructivist learning theory and the PERMA+IT framework of positive psychology in outdoor higher education studies.
Jinsheng (Jason) Zhu, Qideng Mo
doaj   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

open access: yesAdvanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen   +8 more
wiley   +1 more source

Destination Choice Models for Rock Climbing in the Northeast Alps: A Latent-Class Approach Based on Intensity of Participation [PDF]

open access: yes
Practitioners of outdoor sports, such as rock-climbers, are likely to exhibit preference heterogeneity that depends on the ‘keenness’ with which such sports are practiced.
Mara Thiene, Riccardo Scarpa
core  

ALEXANDER PIRATINSKY – A LEADING SPECIALIST IN ROCK CLIMBING IN RUSSIA AND THE WORLD

open access: yesФизическая культура. Спорт. Туризм. Двигательная рекреация, 2020
A. E. Piratinsky is one of the leading experts in Russia and the world on the theory, methods of training athletes and organizing sports events in rock climbing of the highest rank.
Lyudmila Vladimirovna Moiseeva
doaj  

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Effects of Rock Climbers on Vegetative Cover, Richness and Frequency in the Boulder Front Range, Colorado [PDF]

open access: yes, 2013
The Boulder Front Range offers some of the finest rock climbing in North America. As a result many rock climbers find their way into the remote cliff regions of the Front Range (Climbing Management Guide). These areas often serve as refugia for a variety
Holzman, Ryan
core   +2 more sources

Uncover rock-climbing fish's secret of balancing tight adhesion and fast sliding for bioinspired robots. [PDF]

open access: yesNatl Sci Rev, 2023
Tan W   +9 more
europepmc   +1 more source

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