Results 141 to 150 of about 124,943 (294)
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Spartan Daily, November 7, 2000 [PDF]
, 2000 Volume 115, Issue 48https://scholarworks.sjsu.edu/spartandaily/9615/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +6 more sources
Patterns of traumatic outdoor rock-climbing injuries in Sweden between 2008 and 2019. [PDF]
J Exp Orthop, 2021 Identeg F +4 more
europepmc +1 more source
Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs
Advanced Science, EarlyView.Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng +6 more
wiley +1 more source
Female excellence in rock climbing likely has an evolutionary origin. [PDF]
Curr Res Physiol, 2021 Carroll C.
europepmc +1 more source
Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Recreation Benefits of U.S. Parks [PDF]
, 2007 Over 90 percent of people living in the United States participate in some type of outdoor recreation, from walking the dog to rock climbing. These activities increase a person’s well-being and are examples of recreation benefits.
Kaval, Pamela
core +1 more source
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab +14 more
wiley +1 more source
MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion
Advanced Science, EarlyView.ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong +9 more
wiley +1 more source