Results 41 to 50 of about 7,673 (292)
Physiology of sport rock climbing [PDF]
British Journal of Sports Medicine, 2004 Rock climbing has increased in popularity as both a recreational physical activity and a competitive sport. Climbing is physiologically unique in requiring sustained and intermittent isometric forearm muscle contractions for upward propulsion. The determinants of climbing performance are not clear but may be attributed to trainable variables rather ...
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Common neuromusculoskeletal injuries amongst rock climbers in the Western Cape
South African Journal of Physiotherapy, 2015 Background: Rock climbing is an extreme sport that is fast gaining interest in the Western Cape. Due to the physical nature of the sport, climbers often suffer neuromusculoskeletal (NMS) injuries.
Liezel Wegner +5 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
The Journal of the Fell and Rock Climbing Club of the English Lake District. [PDF]
, 1907 Notes from a little-known Coleridge / A. P. Rossiter, pp. 30-38, v. 17, no.
Fell and Rock Climbing Club of the English Lake District.
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
An investigation into the place meanings of recreational climbers at an indoor rock climbing venue [PDF]
, 2018 Indoor rock climbing venues were originally designed as a training site for outdoor rock climbers. However, more recently these venues have been used by climbers who have chosen to remain indoors for the experiences that these sites provide. In addition,
Lewis, P.
core
Research on the Value of Rock-Climbing [PDF]
, 2011 This article discussing the value of Rock-Climbing utilizes literature material method, the logical analytic method, induction and deduction methods.
Xian Rong Qiu
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BMJ Open, 2023 Introduction Rock climbing is a rapidly growing sport in which performance may be affected by participant’s weight and leanness, and there may be pressure on athletes with respect to their eating behaviour and body weight.
Ulrika Tranaeus +6 more
doaj +1 more source