Results 221 to 230 of about 380,756 (310)

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Influence of roof cutting depth on stability of gob side entry in thick coal seams with a bulky limestone roof. [PDF]

Sci Rep
Chai Y, Wang M, Meng L, Wang C, Liang Z, Yang Y, Liu J.   +6 more
europepmc   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Research on the type and expansion mechanism of internal cracks in rocks under the action of PDC. [PDF]

Sci Rep
Liang Y, Du B, Ren J, Feng S.
europepmc   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

An Intelligent Joint Identification Method and Calculation of Joint Attitudes in Underground Mines Based on Smartphone Image Acquisition. [PDF]

Sensors (Basel)
Li G, Zhu J, Jin C, Mao X, Wang Q.
europepmc   +1 more source

Mitigating the Rock‐Salt Phase Transformation in Disordered LNMO Through Synergetic Solid‐State AlF3/LiF Modifications

Advanced Science, EarlyView.
The transition between the spinel and rock‐salt phases induces irreversible structural changes in disordered LiNi0.5Mn1.5O4, thereby preventing it from fully releasing its electrochemical capacity during charge/discharge cycling. Abstract High‐voltage disordered spinel LiNi0.5Mn1.5O4 is a promising cathode material for high power density in lithium‐ion
Xingqi Chang, Carlos Escudero, Ashley P Black, Sharona Horta, Elías Martínez, Xuan Lu, Jordi Llorca, Maria Ibáñez, Jordi Jacas Biendicho, Andreu Cabot   +9 more
wiley   +1 more source

Overburden movement laws in thin bedrock workfaces under thick backfilled loose bodies. [PDF]

Sci Rep
Zheng W, Wei C, Guo S, Zhuang Z, Shi C.
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Research on the mechanism and technology of close range coal seam support and roof cutting collaborative lane control. [PDF]

Sci Rep
Huang W, Liu Y, Zhao T, Sui L, Chu X, Zhu L.   +5 more
europepmc   +1 more source