Results 21 to 30 of about 26,094 (264)

Toward the precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis

BMC Medical Genomics, 2018
Background Breast cancer is the most common type of invasive cancer in woman. It accounts for approximately 18% of all cancer deaths worldwide. It is well known that somatic mutation plays an essential role in cancer development. Hence, we propose that a
Yifan Zhang, William Yang, Dan Li, Jack Y Yang, Renchu Guan, Mary Qu Yang   +5 more
doaj   +1 more source

Stress effect & scale effect on shear properties of double saw-tooth rock joint surface

Applied Rheology, 2021
The shear properties of rock joint control the stability of rock and have an important impact on natural disasters such as landslides and debris flow. In order to study the stress effect and scale effect of shear properties of double saw-tooth rock joint,
Luo Zhanyou, Jiang Mingyao, Mo Linfei, Zou Baoping, Huang Man   +4 more
doaj   +1 more source

Evolution Characteristics of Plastic Zone in Jointed Rock Mass of High-Temperature Hydraulic Tunnel

Applied Sciences, 2023
The evolution characteristics and the extent of the plastic zone in rock mass can reflect the failure characteristics and destruction degree of a hydraulic tunnel.
Kangbin Li, Haibo Jiang, Gang Wei, Pengfei Xiang   +3 more
doaj   +1 more source

Experimental and Numerical Study of the Uniaxial Compressive Stress-Strain Relationship of a Rock Mass with Two Parallel Joints

Archives of Civil Engineering, 2019
A “rock bridge”, defined as the closest distance between two joints in a rock mass, is an important feature affecting the jointed rock mass strength.
Xiong L. X., Yuan H. Y., Zhang Y., Zhang K. F., Li J. B.   +4 more
doaj   +1 more source

IMAGE ANALYSIS FOR MODELLING SHEAR BEHAVIOUR

Image Analysis and Stereology, 2011
Through laboratory research performed over the past ten years, many of the critical links between fracture characteristics and hydromechanical and mechanical behaviour have been made for individual fractures.
Philippe Lopez, Joëlle Riss, Sylvie Gentier, Rock Flamand, Guy Archambault, Soizic Bouvet   +5 more
doaj   +1 more source

THE SURVEY AND THE ANALYSIS OF ROCK JOINT AND THE DETERMINATION OF JOINTED ROCK MASS MODEL

Doboku Gakkai Ronbunshu, 1996
原位置においてボーリング孔壁観察を行い, 得られた画像データをもとに不連続面の位置, 走向・傾斜, 開口幅等を画像処理により求めた. これらの結果を解析することにより, 2種類の不連続性岩盤のモデル化を行った. 一つは, 方向分析によって得られる不連続面群を用いた不連続体モデルである. 本研究では, 頻度, 面積, 開口幅を考慮した不連続面群の相対重要度を比較するパラメータの提案を行い, 実際の計測結果に適用を行った. もう一つは, 地質構造や不連続面の開口幅を考慮にいれて求めるき裂頻度をもとにした擬似連続体モデルの提案を行った. これにより, 変形性や透水性を検討する解析モデルや, ジオトモグラフィー解析などの精度向上に貢献する初期モデルの構築に利用できるものと考える.
Chikaosa Tanimoto, Kiyoshi Kishida, Koji Tabata, Yoichi Yoshizu, Kimihiko Kunii   +4 more
openaire   +2 more sources

Single-Cell Transcriptomic Analysis Unveils Key Regulators and Signaling Pathways in Lung Adenocarcinoma Progression

Biomedicines
Background: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality despite advances in treatments, necessitating more effective therapeutic strategies.
Jialu Ma, Caleb McQuay, John Talburt, Amit K. Tiwari, Mary Qu Yang   +4 more
doaj   +1 more source

Flow Chemistry as an Enabling Technology for Process-Intensified Amination Reactions: A Decadal Review

Molecules
Amines are indispensable structural motifs in pharmaceuticals, agrochemicals, functional materials, and beyond, driving continuous demand for efficient synthetic methods.
Feng Zhou, Yijun Zhou, Pan Wang, Yanxing Li, Jin Li, Haiqing Xu, Chuansong Duanmu   +6 more
doaj   +1 more source

Characterizing the Tumor Microenvironment and Its Prognostic Impact in Breast Cancer

Cells
The tumor microenvironment (TME) is crucial in cancer development and therapeutic response. Immunotherapy is increasingly recognized as a critical component of cancer treatment.
Wenjuan Zhang, Alex Lee, Amit K. Tiwari, Mary Qu Yang   +3 more
doaj   +1 more source

Numerical investigations of rock bridge effect on open pit slope stability

Journal of Rock Mechanics and Geotechnical Engineering, 2019
In this study, the effect of rock bridges on rock slope stability was investigated by incorporating non-persistent joint networks in numerical models, and the critical profiles of an open pit mine were analysed.
C. Romer, M. Ferentinou
doaj   +1 more source