Results 101 to 110 of about 111,840 (308)
Advanced Science, EarlyView.This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang +6 more
wiley +1 more source
Effect of Varying Normal Stiffness on Soft Rock Joints under Cyclic Shear Loads. [PDF]
Materials (Basel), 2023 Niktabar SMM +3 more
europepmc +1 more source
Theoretical Methods for Wave Propagation across Jointed Rock Masses [PDF]
, 2018 Different methods are presently available for the analysis of wave propagation across jointed rock masses with the consideration of multiple wave reflections between joints. These methods can be divided into two categories.
Barla, G. +4 more
core
Advanced Science, EarlyView.ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
Study on the Initiation of Interface Crack in Rock Joints. [PDF]
Materials (Basel), 2022 Chen X, Gao W, Ge S, Zhou C.
europepmc +1 more source
An experimental study on strength behaviour of Jointed Rock Mass through modelling under uniaxial compression tests [PDF]
, 2008 Stability analysis of a rock mass is an important and complicated problem related to the safety of engineering buildings. One of the major tasks of engineering geomechanics is to evaluate the rock mass stability both qualitatively and quantitatively. The
Teja, P
core
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Investigating the Effects of Cement and Polymer Grouting on the Shear Behavior of Rock Joints. [PDF]
Polymers (Basel), 2022 Abolfazli M +3 more
europepmc +1 more source
Shearing tests with continuously increasing normal stress [PDF]
, 2006 In the conventional shearing tests the normal force or the normal stiffness are kept constant during the experiment. Sliding under constant normal load occurs in slopes if the environment is not changing during the process.
Ván, Péter, Vásárhelyi, Balázs
core +1 more source
Integrating Spatial Proteogenomics in Cancer Research
Advanced Science, EarlyView.Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source