Results 101 to 110 of about 12,048 (309)

Effect of Varying Normal Stiffness on Soft Rock Joints under Cyclic Shear Loads. [PDF]

open access: yesMaterials (Basel), 2023
Niktabar SMM   +3 more
europepmc   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

open access: yesAdvanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan   +5 more
wiley   +1 more source

Shear failure in rock using different constant normal load

open access: yes, 1999
SEILDEL – HABERFIELD’s [1] work was based on the analysis of the regular triangular asperities and assumed that the asperities were rigid. They used normal stiffness shear stress (CNS) to measure the joint dilatation rate and extended the LADANYI ...
Vásárhelyi, Balázs
core  

Laboratory tests on shotcrete-rock joints in direct shear, tension and compression

open access: yes, 2005
A series of laboratory tests was performed on cemented shotcrete-rock joints to investigate the strength and stiffness of the interfaces, while simulating field conditions as close as possible.
Malmgren, Lars   +2 more
core   +1 more source

The cohesive frictional crack model applied to the analysis of the dam-foundation joint [PDF]

open access: yes, 2010
The mechanical behaviour of dam-foundation joints plays a key role in concrete dam engineering since it is the weakest part of the structure and therefore the evolutionary crack process occurring along this joint determines the global load-bearing ...
Barpi, Fabrizio, Valente, Silvio
core   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Strength of Rock-Like Specimens with Pre-existing Cracks of Different Length and Width [PDF]

open access: yes, 2016
Discontinuities play a key role in the failure process of rock and rock mass. Small fractures can decrease the strength of rock while large-scaled joints can have a significant effect on the overall stability of rock mass (Eberhardt et al.
Yeung, Chong   +3 more
core   +1 more source

Facile Fabrication of Low‐Impedance, Highly Conformal Epidermal Electrodes Based on Laser‐Induced Graphene–Silver Nanocomposites

open access: yesAdvanced Science, EarlyView.
A facile laser‐induced graphene–silver nanocomposite strategy enables ultrathin epidermal electrodes with low impedance, high conductivity, and excellent mechanical robustness. The porous LIG–Ag conductive network mechanically interlocked with SEBS provides stable, motion‐resistant biopotential monitoring, enabling high‐fidelity ECG, EMG, and EEG ...
Jiuqiang Li   +6 more
wiley   +1 more source

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