Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Spalling Criterion of Hard Brittle Rock Mass Based on Dilatation Lateral Strain. [PDF]
Li H +5 more
europepmc +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Numerical simulation of blasting behavior of rock mass with cavity under high in-situ stress. [PDF]
Rong H, Li N, Cao C, Wang Y, Li J, Li M.
europepmc +1 more source
Inspired by nature's competitive maneuvers, this study introduces a combustion‐driven soft actuator that powers a multi‐modal “Jump‐and‐Fly Catbot” (JFC). With millisecond response, high‐force output (over 70 times its weight) and precise control (error within 5%), the robot can jump, fly, hover, and escape from challenging environments, achieving ...
Hongkuan Ma +4 more
wiley +1 more source
Shear damage mechanisms of jointed rock mass: a macroscopic and mesoscopic study. [PDF]
Wang G +6 more
europepmc +1 more source
Evaporation‐Driven Solutal Marangoni Control of Rayleigh–Taylor Instability in Inverted Films
Inverted liquid films, like paint on a ceiling, are inherently unstable under gravity. This work shows that selective evaporation in volatile binary mixtures generates solutal Marangoni stresses that either suppress or amplify the Rayleigh Taylor instability.
Minwoo Choi, Hyejoon Jun, Hyoungsoo Kim
wiley +1 more source
The grouting plugging mechanism of layered jointed rock mass considering the time-varying yield stress of grout. [PDF]
Yalei Z +5 more
europepmc +1 more source
Mechanism of Rock Mass Detachment Using Undercutting Anchors: A Numerical Finite Element Method (FEM) Analysis. [PDF]
Wójcik A +5 more
europepmc +1 more source

