Results 191 to 200 of about 112,262 (303)

Regulation of Insurance Under the McCarran Act [PDF]

, 1950
Donovan, James B.
core   +2 more sources

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Study on the mechanical properties and permeability evolution of sandstone under cyclic loading and unloading stress-seepage coupling. [PDF]

Sci Rep
Liu Z, Zeng H, Liu G, Zhang Q, Yang X, Xu S.   +5 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Rockburst grade evaluation and parameter sensitivity analysis based on SSA-PNN framework: Considering rock mass strength. [PDF]

PLoS One
Zhou X, Jiang Y, Wang Z, Wang Y.
europepmc   +1 more source

Evaporation‐Driven Solutal Marangoni Control of Rayleigh–Taylor Instability in Inverted Films

Advanced Science, EarlyView.
Inverted liquid films, like paint on a ceiling, are inherently unstable under gravity. This work shows that selective evaporation in volatile binary mixtures generates solutal Marangoni stresses that either suppress or amplify the Rayleigh Taylor instability.
Minwoo Choi, Hyejoon Jun, Hyoungsoo Kim
wiley   +1 more source

Collaborative optimization of the Mathews stability graph method and numerical simulation for the limit exposure area in stope. [PDF]

Sci Rep
You C, Hu J, Li J, Zhang J, Qi Z.
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

A multiscale comprehensive index for evaluating the development level of surface granite discontinuities. [PDF]

PLoS One
Liu G, Wei X, Hou Z.
europepmc   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

Advanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang, Weiyong Song, Heng Yin, Yi Wang, Yi Zou, Yuling Li, Yue Luo, Chao Xiang, Xiaoqin Liu, Yan Xiong, Yong Wang, Ke Jiang   +11 more
wiley   +1 more source