Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source
Feasibility of a mobile health intervention to motivate adolescent fitness and high-intensity exercise adherence (Motivating Adolescent Fitness (MOTAFIT)): protocol for a randomised controlled trial. [PDF]
Koep JL +5 more
europepmc +1 more source
Leveraging the multidimensional self‐catalytic merits of the alkali‐polyphenol synergistic self‐catalytic platform, this work delineates the intrinsic mechanism governing the regulation of hydrogel properties and puts forward an innovative design paradigm for frost‐tolerant electrode materials, providing critical scientific insights and technical ...
Mengting Zhou +10 more
wiley +1 more source
Optimization study on transverse mining zoning during the capacity expansion stage of nearly horizontal open-pit coal mines. [PDF]
Wen Y +5 more
europepmc +1 more source
Unsaturated Coordination Oxygen in Zn─V─O Vacancy Clusters Enables Superb Zinc Storage Capability
Zn3(VO4)2 with Zn─V─O vacancy clusters was synthesized and innovatively applied as cathode material in aqueous Zn‐ion batteries. In‐situ XRD, HRTEM and ab initio molecular dynamics simulations unveil the double reaction mechanism of zinc ions. Adsorption of zinc ions on unsaturated coordination O and H+ on O in ‐VO4 contributes to the main capacity. It
Yulong Chi +8 more
wiley +1 more source
Addressing grading bias in rock climbing: machine and deep learning approaches. [PDF]
O'Mara B, Mahmud MS.
europepmc +1 more source
Bioinspired Morphology‐Decoupled Soft Gripper with Enhanced Bidirectional Grasping Capability
Inspired by biological predation, a novel gripper decouples cross‐modal grasping via dual morphological configurations. Synergistically integrating hybrid rigid and soft coupled fingers with a metamaterial palm, the system performs active compliant grasping for static objects and passive cage capture for dynamic targets.
Yedong Huang +4 more
wiley +1 more source
Prediction of rock type from physical and mechanical properties by data mining implementations. [PDF]
Bayram F.
europepmc +1 more source
III‐nitride semiconductors have revolutionized optoelectronics, enabling transformative technologies such as high‐efficiency LEDs and lasers. However, their use in intersubband optoelectronics has remained limited. This work marks an important step forward by demonstrating highly coherent inter‐well resonant tunneling injection in III‐nitride ...
Jimy Encomendero +6 more
wiley +1 more source
Study on comprehensive landslide risk zoning method in open pit mines under multi factor coupling effects. [PDF]
Jia L, Cui Y, Cao L, Chen X, Liu X.
europepmc +1 more source

