Results 41 to 50 of about 37,255 (261)

Gradation and stress transmission mechanism of mixed backfill in the waste dump

open access: yes矿业科学学报
The structural stability of waste dumps is critically important to the safety of mine production. Taking the mixed tailings-waste rock dump of a specific mine as the research object, this study systematically analyzed the particle gradation ...
ZHANG Xiaodong   +3 more
doaj   +1 more source

Effects of ground rock phosphate and elemental S on yield and P uptake of maize in western Kenya

open access: yes, 1981
The effect on maize yields of ground rock phosphate, alone or mixed with sulphur in either of two proportions, and of single-superphosphate, was measured at five consecutive harvests.
Bromfield, A. R.   +2 more
core   +1 more source

Study on chemical characteristics and evolution law of groundwater in Taigemiao Mining Area

open access: yesMeitan kexue jishu, 2023
Taigemiao Mining Area is rich in coal resources, but water resources are scarce and the ecological environment is fragile, and the use of hydrogeochemical methods to carry out research on the chemical characteristics and evolution law of groundwater in ...
Haixiang LI   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Incorporation of fault rock properties into production simulation models [PDF]

open access: yes, 2005
This thesis has two aims. First, to investigate the importance of incorporating the multiphase flow properties of faults into production simulation models.
Al-Busafi, Bader
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mechanical behavior of mixed rock-ice deposits in high-latitude mountainous areas

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
The mixed rock-ice deposits in high-latitude areas usually come from the accumulation of rock-ice avalanches. Melting tests and temperature-controlled triaxial tests were conducted on rock-ice mixture samples with varying volumetric ice contents (0.25, 0.
Wenbin Chang   +3 more
doaj   +1 more source

Biomarker characteristics of Montney source rock, British Columbia, Canada

open access: yesHeliyon, 2021
Montney Formation (MF) source rock located in northeastern British Columbia (BC), Canada, was analyzed to determine its depositional conditions and organic matter source input other than to determine their level of thermal maturity. The high total sulfur
Azzam Barham   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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