Results 141 to 150 of about 20,638 (305)

Characterization and Stability Analysis of Rock Mass Discontinuities in Layered Slopes: A Case Study from Fushun West Open-Pit Mine

open access: yesApplied Sciences
Discontinuities exist widely in high rock slopes and threaten their stability at all times. To accurately characterize the information of rock mass discontinuities in high slopes, the layered rock slope on the north side of the Fushun West Open-pit Mine ...
Ming Li   +5 more
doaj   +1 more source

Large‐Scale Growth of Self‐Poled Ferroelectric Rashba Semiconductor α‐GeTe(111) Thin Films: A Crucial Step Towards Future CMOS‐Compatible Ferroelectric Spintronic Devices

open access: yesAdvanced Science, EarlyView.
Ferroelectric Rashba semiconductors promise ultralow‐power devices but lack industry‐quality films. This work demonstrates CMOS‐compatible fabrication of high‐quality α‐GeTe(111) films via magnetron sputtering, enabled by a 5 nm Sb2Te3 seed layer. Structural and ferroelectric analyses show robust, switchable polarization comparable to MBE films, paving
Jules Lagrave   +14 more
wiley   +1 more source

Outstanding TC Enhancement in 5d–3d Y2NiIrO6 by Compression

open access: yesAdvanced Science, EarlyView.
Double perovskite Y2NiIrO6 with half filed 3d eg–5d t2g configuration, exhibits first experimental example of pressure‐enhanced magnetic interaction in iridate and iridate‐related systems. Its Curie temperature increase from 192 to 243 K at 17 GPa. Herein, the orthogonal eg–t2g pathway remains robust even under compression‐induced lattice distortion ...
Zheng Deng   +18 more
wiley   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

open access: yesAdvanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng   +18 more
wiley   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

open access: yesAdvanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang   +10 more
wiley   +1 more source

The role of mass-movement in shore platform development along the Gisborne coastline, New Zealand [PDF]

open access: yes, 1968
Tidal shore platforms form a conspicuous part of the coastal scenery north of Gisborne, New Zealand. Some of these platforms are being extended landward under present-day conditions. Present widening results primarily from cliff-retreat by mass-movement.
Davidson, C.F., McLean, R.F.
core  

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

open access: yesAdvanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal   +9 more
wiley   +1 more source

Rock mechanics studies to improve intact rock block exploitation and slope stability conditions in a quarry basin [PDF]

open access: yes, 1996
This paper deals with rock mechanics studies for the optimization of the design lay-out in the Osceola Valley ornamental stone basin (north-west Italy). The exploitation planning has to consider the different structural and geological situations observed
DEANGELI, CHIARA   +4 more
core  

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu   +8 more
wiley   +1 more source

Numerical analysis of the failure of heavily jointed rock slopes using PFC2D

open access: yes工程科学与技术, 2010
:The post-failure behavior of slopes is very important for the hazard map producing and risk assessment of landslide. The kinematic process of heavily jointed rock slopes is simulated using a 2D discrete element model (PFC2D code). The numerical model is
lixinpo
doaj  

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