Millimeter‐Scale Dual‐Opposing RNA‐Gradient Hydrogel for Interfacial Gene Silencing
A branched microfluidic platform enables the fabrication of millimeter‐scale hydrogels with dual‐opposing RNA‐gradients for precise spatial control of cell gene expression. This device allows for the generation of multiple constructs at once, offering potential for future engineering of complex tissue interfaces with improved physiological relevance ...
Tyler Hoffman +11 more
wiley +1 more source
Genomic characterization of antimicrobial resistance and virulence determinants in <i>Salmonella</i> Infantis isolated from human, food, and animal sources. [PDF]
Han J, Tang E, Zhao S, Foley SL.
europepmc +1 more source
Engineering an Optogenetic pH‐Modulator in Bacteria
ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang +7 more
wiley +1 more source
Practices of North American pediatric gastroenterologists in the management of celiac disease-A survey study. [PDF]
Khan HH, Kumar S, Lyons H.
europepmc +1 more source
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang +14 more
wiley +1 more source
Chagas Disease, an Endemic Disease in the United States. [PDF]
Beatty NL +4 more
europepmc +1 more source
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab +14 more
wiley +1 more source
Comprehensive input models and machine learning methods to improve permeability prediction. [PDF]
Davari MA, Kadkhodaie A.
europepmc +1 more source
MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong +9 more
wiley +1 more source
First record of Panstrongylus megistus (Burmeister, 1835) (Hemiptera, Reduviidae, Triatominae) from Ilha Grande, Rio de Janeiro, Brazil. [PDF]
Seabra AP +5 more
europepmc +1 more source

