Results 21 to 30 of about 49,366 (268)

Experimental Study of the Seismic Performance of a Prefabricated Frame Rocking Wall Structure

open access: yesBuildings, 2022
This paper proposes a prefabricated frame rocking wall (PFRW) structure system in which beams, columns, and rocking walls are all prefabricated components.
Fuwen Zhang   +5 more
doaj   +1 more source

Practical research of free standing rack (Development of seismic evaluation method)

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Under earthquake condition, the response of the free standing rack is nonlinear and involves complex combination of motion, such as sliding, rocking, twisting, and impacts between the fuel assemblies and the rack cells and between the pool floor and the ...
Akihisa IWASAKI   +6 more
doaj   +1 more source

Comparative Assessment of Two Rocking Isolation Techniques for a Motorway Overpass Bridge

open access: yesFrontiers in Built Environment, 2017
Rocking isolation of structures is evolving as an alternative design concept in earthquake engineering. The present paper investigates the seismic performance of an actual overpass bridge of the Attiki Odos motorway (Athens, Greece), employing two ...
Athanasios Agalianos   +4 more
doaj   +1 more source

Free Rocking of a Rigid Block on a Flexible Structure with Non-Smooth Contact Dynamics

open access: yesApplied Sciences
When structures are subjected to dynamic loading, such as that caused by an earthquake or working machinery, the rocking behavior of objects located on parts of the loaded structure plays an important role in addressing the protection and stability of ...
Teo Mudrić   +3 more
doaj   +1 more source

Hypothesis: The Vestibular and Cerebellar Basis of the Mal de Debarquement Syndrome

open access: yesFrontiers in Neurology, 2018
The Mal de Debarquement syndrome (MdDS) generally follows sea voyages, but it can occur after turbulent flights or spontaneously. The primary features are objective or perceived continuous rocking, swaying, and/or bobbing at 0.2 Hz after sea voyages or 0.
Bernard Cohen   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Closed-form overturning limit of rigid block under critical near-fault ground motions

open access: yesFrontiers in Built Environment, 2016
A closed-form limit on the input level of the double impulse as a substitute of a near-fault ground motion is derived for the overturning of a rigid block.
Kunihiko eNabeshima   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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