Results 31 to 40 of about 49,366 (268)

Performance of rocking systems on shallow improved sand: Shaking table testing

Frontiers in Built Environment, 2015
Recent studies have highlighted the potential benefits of inelastic foundation response during seismic shaking. According to an emerging seismic design scheme, termed rocking isolation, the foundation is intentionally under–designed to promote rocking ...
Angelos eTsatsis, Ioannis eAnastasopoulos   +1 more
doaj   +1 more source

Data-Driven Modeling of Peak Rotation and Tipping-Over Stability of Rocking Shallow Foundations Using Machine Learning Algorithms

Geotechnics, 2022
The objective of this study is to develop data-driven predictive models for peak rotation and factor of safety for tipping-over failure of rocking shallow foundations during earthquake loading using multiple nonlinear machine learning (ML) algorithms and
Sivapalan Gajan
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Dynamic Response of Ancient Dowel-Connected Multi-Drum Columns: A 3D Finite Element Study of Friction Effects

Buildings
The dynamic response of ancient multi-drum columns, commonly found in historical monuments, is characterized by complex nonlinear mechanisms including rocking, sliding, and wobbling.
Olympia K. Panagouli, Maria Kafetsi
doaj   +1 more source

MOBILE INFORMATION SYSTEM PENDATAAN HASIL PENGOLAHAN BIJI TIMAH DENGAN ALAT MEJA GOYANG PADA PT TIMAH TBK

Jurnal Sisfokom, 2021
The high demand for tin mining commodities has pushed the development of mining product processing technology quite significantly. However, the more difficult it is to obtain available reserves and the lower the processed Tin content, the lower the ...
Anisah, Herfani Tri Nurpebri, Sarwindah, Yurindra   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A method for optimizing and controlling rocking drillstring–assisted slide drilling

Natural Gas Industry B
Rocking the drillstring at the surface during slide drilling is a common method for reducing drag when drilling horizontal wells. However, the current methods for determining the parameters for rocking are insufficient, limiting the widespread use of ...
Yabin Zhang, Jian Lu, Binfeng Guo, Xueying Wang, Feifei Zhang   +4 more
doaj   +1 more source

Unbonded Post-tensioned Precast Concrete Walls With Rocking Connections: Modeling Approaches and Impact Damping

Frontiers in Built Environment, 2021
Over the past two decades, precast concrete members have been utilized in seismically resilient structures. In developing these structures, different techniques have been used for connecting the precast members to the foundation. In building construction,
Dimitrios Kalliontzis, Maryam Nazari
doaj   +1 more source

Rock's pill that rocked the world

South African Medical Journal, 2010
I was a rookie doctor on the goldmines in the early 1960s. Part of my duties was to look after the families in the villages of the Anglo American mines at Welkom in the Free State. Their invariably large numbers of children prompted me to enquire whether they wished to have assistance in family planning.
openaire   +3 more sources