Results 21 to 30 of about 20,104 (207)

Seismic Performance Analysis of Tuned Mass Rocking Wall (TMRW)-Frame Building Structures

open access: yesBuildings, 2021
A tuned mass rocking wall (TMRW) is a passive control device that combines the merits of a traditional tuned mass damper (TMD) and a traditional rocking wall (RW).
Andong Wang   +3 more
doaj   +1 more source

Fragility Analysis of Step-Terrace Frame-Energy Dissipating Rocking Wall Structure in Mountain Cities

open access: yesApplied Sciences
Rocking walls can control the overall deformation pattern and the distribution of plastic energy dissipation in structures, suppressing the occurrence of weak layers.
Youfa Yang, Yingwei Jia, Hongshen Jin
doaj   +1 more source

Development of Rocking Isolation for Response Mitigation of Elevated Water Tanks under Seismic and Wind Hazards

open access: yesShock and Vibration, 2020
Elevated water tanks are categorized as strategic components of water supply systems in modern urban management. Past earthquake events have revealed the high vulnerability of these structures. This paper investigates the development of rocking isolation
Hassan Alemzadeh   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

A Simplified Mechanical Model for Rocking Structures on Compliant Foundations

open access: yesApplied Mechanics
Housner’s classical rocking model assumes a rigid base, which often leads to inaccurate seismic assessments under real–world soil conditions. This study quantitatively establishes the applicability limits of the rigid–base assumption and defines a ...
Baojun Yuan   +2 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Assessment of Soft-First-Floor Structures Reinforced by Rocking Frame Based on Seismic Resilience

open access: yesBuildings
As a no-disturbance integrated-retrofitting technique, an external rocking frame was widely used on reinforced concrete (RC) structures. Yet, with the increasing demand for seismic strengthening of existing buildings, it has become a concern to evaluate ...
Shaofei Jiang   +5 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Seismic Isolation of Fragile Pole-Type Structures by Rocking with Base Restraints

open access: yesBuildings
Pole-type structures are vulnerable to earthquake events due to their slender shapes, particularly porcelain cylindrical equipment in electrical substations, which has inherent fragility and low strength in its materials.
Sheng Li   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

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