Results 61 to 70 of about 900,993 (312)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

КАМЕННЫЕ ПЛИТЫ ИЗ СКИФСКИХ ЗАХОРОНЕНИЙ ЛЕВОБЕРЕЖЬЯ НИЖНЕГО ДНЕСТРА [PDF]

Материалы по археологии и истории античного и средневекового Причерноморья
В статье анализируются 43 каменные плиты из скифских захоронений левобережья Нижнего Днестра V—II вв. до н.э. Они происходят из мужских и женских погребений и использовались, вероятно, в качестве столов, на которые ставились различные предметы.
Хотылев, А.О., Майоров, А.А., Синика, В.С.   +2 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Determination of total and non-carbonate carbon in rock samples by a method using infrared absorption [PDF]

Bulletin of the Geological Society of Finland, 1990
Total and non-carbonate carbon were determined by a method using infrared absorption in 20 international geological reference samples, 13 in-house reference samples and 13 other rock samples.
R.J. Saikkonen, I.A. Rautiainen
doaj   +1 more source

Rocking pneumonia

Pneumonia, 2017
Ever since Chuck Berry coined the term "rocking pneumonia" in his 1956 song "Roll over Beethoven", pneumonia has been mentioned frequently in modern blues and rock songs. We analyzed the lyrics of these songs to examine how various elements of pneumonia have been represented in popular music, specifically the cause of pneumonia, the risk groups ...
Ger T. Rijkers, Maria Rodriguez Gomez
openaire   +3 more sources

When do we need pan-global freeze to explain ^(18)O-depleted zircons and rocks? [PDF]

, 2011
Rocks with δ^(18)O values of less than 5‰ SMOW (Standard Mean Ocean Water) contain oxygen derived from ∼0‰ seawater or meteoric (rain or melted snow,
Bindeman, Ilya
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Hydrocarbon potential of Eastern View Group Reservoir Rocks, Bass Basin, Australia. [PDF]

, 2011
Hydrocarbon exploration to-date in the Bass Basin has focused on Eocene reservoir rocks of the Upper Eastern View Group with limited success. This thesis focuses on the hydrocarbon potential of Middle and Lower Eastern View Group reservoir rocks which ...
Arian, Natt
core   +1 more source

Rupture by damage accumulation in rocks [PDF]

, 2006
The deformation of rocks is associated with microcracks nucleation and propagation, i.e. damage. The accumulation of damage and its spatial localization lead to the creation of a macroscale discontinuity, so-called "fault" in geological terms, and to the
A Buchel, A Guarino, A Johansen, A Lin, AM Boullier, B Gutenberg, B Menendez, B Velde, C Marone, C Nicholson, C Scavia, CA Tang, CA Tang, CAJ Wibberley, CG Bufe, CG Sammis, CH Scholz, CH Scholz, D Amitrano, D Place, D Sornette, DA Lockner, DA Lockner, DA Lockner, David Amitrano, DE Moore, E Bouchaud, E Bouchaud, EM Schulson, F Kun, GCP King, H Nechad, HL Li, IG Main, J Biarez, J Kemeny, J Mori, J Rice, J Schmittbuhl, J Schmittbuhl, J Weiss, J Weiss, JC Jaeger, JVA Keller, JW Rudnicki, K Chen, K Mair, K Michibayashi, K Mogi, LS Costin, M Gerstenberger, P Cowie, P Grassberger, RL Kranz, RP Young, S Zapperi, S Zapperi, SC Jaume, SJD Cox, SR Brown, T Hirata, W Wang, YC Wang, Z Olami, Z Reches   +64 more
core   +4 more sources