Treatment of rocuronium-induced anaphylaxis using sugammadex - A case report - [PDF]
Background Perioperative anaphylaxis is a life-threatening clinical condition characterized by severe respiratory and cardiovascular manifestations. Neuromuscular blocking agents are the most common cause of anaphylaxis during anesthesia.
Sun-Min Kim, Sei-hoon Oh, Seung-Ah Ryu
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Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children [PDF]
BackgroundThe aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children.MethodsAfter loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 ...
Young Hee Shin+8 more
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Rocuronium Bromide Inhibits Inflammation and Pain by Suppressing Nitric Oxide Production and Enhancing Prostaglandin E Synthesis in Endothelial Cells [PDF]
Purpose Rocuronium bromide is a nondepolarizing neuromuscular blocking drug and has been used as an adjunct for relaxation or paralysis of the skeletal muscles, facilitation of endotracheal intubation, and improving surgical conditions during general ...
Sang Bin Baek+7 more
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Pharmacological interventions for acceleration of the onset time of rocuronium: a meta-analysis. [PDF]
Rocuronium is an acceptable alternative when succinylcholine is contraindicated for facilitating the endotracheal intubation. However, the onset time of rocuronium for good intubation condition is still slower than that condition of succinylcholine. This
Jing Dong+4 more
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The antagonistic effect of neostigmine on rocuronium-, clindamycin-, or both-induced neuromuscular blocking in the rat phrenic nerve-hemidiaphragm [PDF]
BackgroundNeostigmine augments clindamycin-induced neuromuscular block and antagonizes rocuronium-induced neuromuscular block; however, it remains unclear whether neostigmine enhances the neuromuscular blocking (NMB) that is caused by combinations of ...
Seung Soo Kim+3 more
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Successful management of rocuronium-induced anaphylaxis with sugammadex: A case report
Although anaphylaxis during anaesthesia is a rare event, neuromuscular blocking drugs are responsible for 62% of anaesthesia-related anaphylaxis. However, sugammadex, a modified gamma-cyclodextrin, can encapsulate rocuronium molecules and cause the rapid
Sheng-Kai Hung+4 more
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The effect of long-term oral dantrolene on the neuromuscular action of rocuronium: a case report [PDF]
Oral dantrolene causes a dose-dependent depression of skeletal muscle contractility. A 52-year-old man treated with oral dantrolene for spasticity after spinal cord injury was scheduled to undergo irrigation and drainage of a thigh abscess under general ...
Jinwoo Jeon+4 more
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Comparison of Intubating Conditions of Two Doses of Rocuronium Bromide with Succinylcholine in Children undergoing Elective Surgeries under General Anaesthesia- A Randomised Control Trial [PDF]
Introduction: Succinylcholine is a muscle relaxant of choice for paediatric intubation due to its fast onset and ultrashort duration of action but it is associated with unwanted side-effects.
Maitri Patel+4 more
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Comparison of injection pain in pediatric population; original versus generic rocuronium
Background: Rocuronium-induced injection pain causes withdrawal movements. These movements may cause accidental disruption of indwelling needles. Generic rocuronium contains low-acid concentration buffer solution compared with original rocuronium.
Fumio Watanabe+2 more
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Intravenous infusion of rocuronium bromide prolongs emergence from propofol anesthesia in rats.
BackgroundNeuromuscular blocking agents induce muscle paralysis via the prevention of synaptic transmission at the neuromuscular junction and may have additional effects at other sites of action. With regard to potential effects of neuromuscular blocking
Kaoru Suzuki+6 more
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