Results 81 to 90 of about 882,412 (385)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Fumigation of Burrowing Rodents with Carbon Monoxide: A Comparison to Alternative Management Options [PDF]

, 2018
Pocket gophers and ground squirrels cause extensive damage to many crops. Pressurized exhaust injection devices are increasingly used for managing these rodents, although no data were available to support their use.
Baldwin, Roger A., Kavermann, Matthew, Meinerz, Ryan, Orloff, Steve B.   +3 more
core  

Making Sense of Rodent Models of Anhedonia

International Journal of Neuropsychopharmacology, 2018
A markedly reduced interest or pleasure in activities previously considered pleasurable is a main symptom in mood disorder and psychosis and is often present in other psychiatric disorders and neurodegenerative diseases. This condition can be labeled as “
S. Scheggi, M. D. De Montis, C. Gambarana   +2 more
semanticscholar   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Preliminary evidence of increased striatal dopamine in a nonhuman primate model of maternal immune activation. [PDF]

, 2019
Women exposed to a variety of viral and bacterial infections during pregnancy have an increased risk of giving birth to a child with autism, schizophrenia or other neurodevelopmental disorders.
Bauman, Melissa D, Carter, Cameron S, Cherry, Simon R, Kukis, David L, Lesh, Tyler A, McAllister, A Kimberley, Rowland, Douglas J, Schumann, Cynthia M, Smucny, Jason   +8 more
core   +2 more sources

Does age matter? The impact of rodent age on study outcomes

Laboratory Animals. Journal of the Laboratory Animal Science Association, 2016
Rodent models produce data which underpin biomedical research and non-clinical drug trials, but translation from rodents into successful clinical outcomes is often lacking. There is a growing body of evidence showing that improving experimental design is
Samuel J. Jackson, Nick A. Andrews, Doug Ball, I. Bellantuono, James Douglas Allan Gray, L. Hachoumi, A. Holmes, J. Latcham, Anja Petrie, P. Potter, A. Rice, A. Ritchie, Michelle Stewart, Carol Strepka, M. Yeoman, Kathryn L Chapman   +15 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Agriculture and forest rodent problems and control in Italy [PDF]

, 1986
Rodent pest problems and their control in Italy are reviewed. Two rats, Rattus norvegicus and Rattus rattus, and the field mouse, Apodemus sylvaticus, are often important pests both in rural and forestry areas.
Santini, Luciano A.
core  

The pan-genome of Lactobacillus reuteri strains originating from the pig gastrointestinal tract [PDF]

, 2015
Background Lactobacillus reuteri is a gut symbiont of a wide variety of vertebrate species that has diversified into distinct phylogenetic clades which are to a large degree host-specific.
Crossman, Lisa C., Goesmann, Alexander, Juge, Nathalie, Mackenzie, Donald A., Roos, Stefan, Swarbreck, David, Walter, Jens, Wegmann, Udo, Zheng, Jinshui   +8 more
core   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source