Results 91 to 100 of about 9,520,639 (370)

In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris [PDF]

open access: yes, 2006
We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus.
Behnke, J.M.   +4 more
core   +3 more sources

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Making Sense of Rodent Models of Anhedonia

open access: yesInternational Journal of Neuropsychopharmacology, 2018
A markedly reduced interest or pleasure in activities previously considered pleasurable is a main symptom in mood disorder and psychosis and is often present in other psychiatric disorders and neurodegenerative diseases. This condition can be labeled as “
S. Scheggi   +2 more
semanticscholar   +1 more source

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

open access: yes, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E   +3 more
core   +2 more sources

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

High levels of infectiousness of asymptomatic Leishmania (Viannia) braziliensis infections in wild rodents highlights their importance in the epidemiology of American Tegumentary Leishmaniasis in Brazil.

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundThe epidemiological significance of wildlife infections with aetiological agents causing human infectious diseases is largely determined by their infection status, contact potential with humans (via vectors for vector-borne diseases), and their
José Ferreira Marinho-Júnior   +7 more
doaj   +1 more source

Rodent control to fight Lassa fever: Evaluation and lessons learned from a 4-year study in Upper Guinea

open access: yesPLoS Neglected Tropical Diseases, 2018
Lassa fever is a viral haemorrhagic fever caused by an arenavirus. The disease is endemic in West African countries, including Guinea. The rodents Mastomys natalensis and Mastomys erythroleucus have been identified as Lassa virus reservoirs in Guinea. In
Almudena Marí Sáez   +6 more
semanticscholar   +1 more source

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

open access: yes, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina   +3 more
core   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

open access: yesAdvanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu   +7 more
wiley   +1 more source

Association Between Autophagy and Neurodegenerative Diseases

open access: yesFrontiers in Neuroscience, 2018
Autophagy is a phylogenetically conserved mechanism that controls the degradation of subcellular constituents, including misfolded proteins, and damaged organelles.
N. Fujikake, M. Shin, S. Shimizu
semanticscholar   +1 more source

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